J.J. Watt has the most tackles for loss in a season, with 39 tackles in 2012.

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Regular season

	NAME	TFL	SEASON	TM	GP	TKL	AST	COMB	SCK	SCKY	INT	INT YDS	INT TD	FF	FR	FR TD
1	J.J. Watt	39	2012	HOU	16	69	12	81	20.5	138.5	0	0	0	4	2	0
2	Myles Garrett M. Garrett	33	2025	CLE	17	43	17	60	23.0	165	0	0	0	3	0	0
3	J.J. Watt	29	2015	HOU	16	57	19	76	17.5	117.5	0	0	0	3	1	0
4	J.J. Watt	29	2014	HOU	16	59	19	78	20.5	140	1	80	1	4	5	1
5	Maxx Crosby M. Crosby	28	2025	LV	15	45	28	73	10.0	50	1	19	0	2	0	0
6	Chandler Jones C. Jones	28	2017	ARI	16	52	7	59	17.0	113	0	0	0	2	0	0
7	Von Miller V. Miller	28	2012	DEN	16	55	13	68	18.5	129.5	1	26	1	6	0	0
8	DeMarcus Ware D. Ware	27	2008	DAL	16	69	15	84	20.0	113	0	0	0	6	1	0
9	DeMarcus Ware D. Ware	26	2011	DAL	16	48	10	58	19.5	124.5	0	0	0	2	1	0
10	Aaron Donald A. Donald	25	2018	LAR	16	41	18	59	20.5	183.5	0	0	0	4	2	0
11	Michael Strahan M. Strahan	24	2001	NYG	16	61	12	73	22.5	177.5	0	0	0	6	1	1
12	Danielle Hunter D. Hunter	23	2023	MIN	17	54	29	83	16.5	120	0	0	0	4	0	0
13	Maxx Crosby M. Crosby	23	2023	LV	17	55	35	90	14.5	100	0	0	0	2	1	0
14	T.J. Watt	23	2020	PIT	15	43	10	53	15.0	112.5	1	0	0	2	0	0
15	Khalil Mack K. Mack	23	2015	OAK	16	57	20	77	15.0	89	0	0	0	2	0	0
16	Justin Houston J. Houston	23	2014	KC	16	60	9	69	22.0	99	0	0	0	4	0	0
17	Robert Quinn R. Quinn	23	2013	STL	16	50	7	57	19.0	145	0	0	0	7	2	1
18	Jason Pierre-Paul J. Pierre-Paul	23	2011	NYG	16	66	20	86	16.5	112	0	0	0	2	0	0
19	Michael Strahan M. Strahan	23	2003	NYG	16	60	15	75	18.5	126.5	0	0	0	3	1	0
20	Kendrell Bell K. Bell	23	2001	PIT	16	69	13	82	9.0	84	0	0	0	1	0	0
21	Brian Burns B. Burns	22	2025	NYG	17	39	28	67	16.5	136	0	0	0	3	1	0
22	Myles Garrett M. Garrett	22	2024	CLE	17	40	7	47	14.0	92	0	0	0	3	1	0
23	Maxx Crosby M. Crosby	22	2022	LV	17	58	31	89	12.5	102	0	0	0	3	1	0
24	Aaron Donald A. Donald	22	2015	STL	16	44	25	69	11.0	59.5	0	0	0	0	1	0
25	J.J. Watt	22	2013	HOU	16	65	15	80	10.5	70.5	0	0	0	4	2	0

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StatMuse has season-level data for tackles for loss going back to the 2001 season.

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J.J. Watt has the most tackles for loss in a season, with 39 tackles in 2012.

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