The San Francisco 49ers have a 21-14 record in the regular season and playoffs against the AFC West at home all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/25/1970 | 1-0 | vs | W 19-14 | 1.000 | 1 | 16 | 362 | 283 | ||||
| 2 | | 49ers | 12/6/1971 | 0-1 | vs | L 17-26 | .000 | 2 | 18 | 331 | 427 | ||||
| 3 | | 49ers | 9/17/1972 | 1-0 | vs | W 34-3 | 1.000 | 4 | 18 | 295 | 258 | ||||
| 4 | | 49ers | 10/27/1974 | 0-1 | vs | L 24-35 | .000 | 3 | 20 | 372 | 297 | ||||
| 5 | | 49ers | 10/7/1979 | 0-1 | vs | L 24-35 | .000 | 3 | 29 | 464 | 310 | ||||
| 6 | | 49ers | 11/18/1979 | 0-1 | vs | L 28-38 | .000 | 4 | 18 | 240 | 369 | ||||
| 7 | | 49ers | 9/12/1982 | 0-1 | vs | L 17-23 | .000 | 2 | 18 | 252 | 255 | ||||
| 8 | | 49ers | 12/11/1982 | 0-1 | vs | L 37-41 | .000 | 5 | 29 | 465 | 538 | ||||
| 9 | | 49ers | 11/17/1985 | 1-0 | vs | W 31-3 | 1.000 | 4 | 24 | 417 | 200 | ||||
| 10 | | 49ers | 11/25/1985 | 1-0 | vs | W 19-6 | 1.000 | 2 | 21 | 376 | 252 | ||||
| 11 | | 49ers | 10/9/1988 | 0-1 | vs | L 13-16 | .000 | 1 | 21 | 417 | 314 | ||||
| 12 | | 49ers | 11/13/1988 | 0-1 | vs | L 3-9 | .000 | 0 | 15 | 219 | 251 | ||||
| 13 | | 49ers | 9/8/1991 | 1-0 | vs | W 34-14 | 1.000 | 4 | 24 | 458 | 326 | 36.4 | 0.0 | ||
| 14 | | 49ers | 12/14/1991 | 1-0 | vs | W 28-14 | 1.000 | 4 | 24 | 408 | 310 | 40.0 | 100.0 | ||
| 15 | | 49ers | 9/5/1994 | 1-0 | vs | W 44-14 | 1.000 | 6 | 24 | 448 | 181 | 40.0 | 100.0 | ||
| 16 | | 49ers | 12/17/1994 | 1-0 | vs | W 42-19 | 1.000 | 6 | 25 | 488 | 334 | 66.7 | 100.0 | ||
| 17 | | 49ers | 1/29/1995 | 1-0 | vs | W 49-26 | 1.000 | 7 | 28 | 455 | 354 | 53.8 | |||
| 18 | | 49ers | 11/23/1997 | 1-0 | vs | W 17-10 | 1.000 | 2 | 19 | 339 | 203 | 30.8 | |||
| 19 | | 49ers | 12/15/1997 | 1-0 | vs | W 34-17 | 1.000 | 4 | 18 | 323 | 237 | 38.5 | |||
| 20 | | 49ers | 10/8/2000 | 0-1 | vs | L 28-34 | .000 | 4 | 28 | 472 | 471 | 60.0 | 0.0 | ||
| 21 | | 49ers | 11/12/2000 | 1-0 | vs | W 21-7 | 1.000 | 3 | 25 | 389 | 294 | 50.0 | |||
| 22 | | 49ers | 9/15/2002 | 0-1 | vs | L 14-24 | .000 | 2 | 18 | 261 | 299 | 61.5 | |||
| 23 | | 49ers | 11/10/2002 | 1-0 | vs | W 17-13 | 1.000 | 2 | 22 | 323 | 256 | 61.1 | 100.0 | ||
| 24 | | 49ers | 10/8/2006 | 1-0 | vs | W 34-20 | 1.000 | 4 | 18 | 330 | 370 | 45.5 | 0.0 | ||
| 25 | | 49ers | 10/15/2006 | 0-1 | vs | L 19-48 | .000 | 2 | 15 | 274 | 421 | 36.4 | 0.0 | ||
| Average | .600 | 3.1 | 21.1 | 370.4 | 314.5 | ||||||||||
| Total | 21-14 | .600 | 107 | 739 | 12,963 | 11,006 | |||||||||
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More 49ers Stats
Team Leaders 
PASS
1,196
Purdy
RUSH
286
McCaffrey
REC
326
Evans
Team Rankings
PPG
30.8
3rd
OPP PPG
18.6
4th
RUSH YDS/G
128.6
8th
PASS YDS/G
239.2
18th
Cardinals
Rams
WAS
ATL
DAL
MIN
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 2 | 1 | .583 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 3 | 1 | .300 | |
| NFC North | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
3 | 2 | 0 | .600 | |
| NFC South | W | L | T | PCT |
3 | 2 | 0 | .600 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 5 | 0 | .167 | |
| NFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 3 | 0 | .500 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 |
Giants
Eagles
Packers
Bears
Lions
Panthers
Saints
Buccaneers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 2 | 0 | .667 | |
2 | 4 | 0 | .333 | |
0 | 5 | 0 | .000 | |
| AFC North | W | L | T | PCT |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
3 | 2 | 0 | .600 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 5 | 0 | .167 | |
| AFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
4 | 2 | 0 | .667 | |
3 | 3 | 0 | .500 | |
0 | 6 | 0 | .000 |
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