o.j. simpson most rushing yards in a game

O.J. Simpson rushed for his most yards in a game against the Lions on November 25, 1976, with 273 yards.

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All-time
Regular season

	NAME	RUSH YDS	DATE	TM		OPP	ATT	YPC	RUSH TD	REC YDS	REC	AVG	REC TD
1	O.J. Simpson	273	11/25/1976	BUF	@	DET	29	9.4	2	0	0		0
2	O.J. Simpson	250	9/16/1973	BUF	@	NE	29	8.6	2	0	0		0
3	O.J. Simpson	227	9/28/1975	BUF	@	PIT	28	8.1	1	0	0		0
4	O.J. Simpson	219	12/9/1973	BUF	vs	NE	22	10.0	1	0	0		0
5	O.J. Simpson	203	12/5/1976	BUF	@	MIA	24	8.5	1	12	2	6.0	0
6	O.J. Simpson	200	12/16/1973	BUF	@	NYJ	34	5.9	1	0	0		0
7	O.J. Simpson	197	11/17/1975	BUF	@	CIN	17	11.6	2	21	2	10.5	0
8	O.J. Simpson	189	10/29/1972	BUF	vs	PIT	22	8.6	1	7	3	2.3	0
9	O.J. Simpson	185	12/14/1975	BUF	@	NE	21	8.8	1	28	2	14.0	0
10	O.J. Simpson	173	9/21/1975	BUF	vs	NYJ	32	5.4	2	5	1	5.0	0
11	O.J. Simpson	171	12/12/1976	BUF	@	BAL	28	6.1	1	18	1	18.0	0
12	O.J. Simpson	171	10/7/1973	BUF	vs	PHI	27	6.3	1	33	3	11.0	0
13	O.J. Simpson	166	10/31/1976	BUF	vs	NYJ	29	5.7	0	0	0		0
14	O.J. Simpson	166	10/14/1973	BUF	vs	BAL	22	7.5	2	0	0		0
15	O.J. Simpson	159	10/12/1975	BUF	@	BAL	32	5.0	1	14	1	14.0	0
16	O.J. Simpson	157	10/29/1973	BUF	vs	KC	39	4.0	2	0	0		0
17	O.J. Simpson	144	10/15/1972	BUF	@	OAK	28	5.1	0	9	2	4.5	0
18	O.J. Simpson	138	10/16/1977	BUF	vs	ATL	23	6.0	0	5	1	5.0	0
19	O.J. Simpson	138	10/5/1975	BUF	vs	DEN	26	5.3	1	0	0		0
20	O.J. Simpson	138	9/24/1972	BUF	vs	SF	29	4.8	0	20	2	10.0	0
21	O.J. Simpson	137	12/2/1973	BUF	@	ATL	24	5.7	0	0	0		0
22	O.J. Simpson	130	10/3/1976	BUF	vs	KC	24	5.4	2	8	1	8.0	0
23	O.J. Simpson	127	10/13/1974	BUF	@	BAL	23	5.5	0	8	1	8.0	0
24	O.J. Simpson	126	10/20/1975	BUF	vs	NYG	34	3.7	1	0	0		0
25	O.J. Simpson	124	11/25/1973	BUF	@	BAL	15	8.3	1	0	0		0

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Results may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.

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38.5

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TEAM	W	L	PCT
Bills	2	0	1.000
Patriots	1	1	.500
Jets	1	1	.500
Dolphins	0	2	.000

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/27	LAC	@	BUF	1:00 PM
Sun 10/4	NE	@	BUF	1:00 PM
Mon 10/12	BUF	@	LAR	8:15 PM
Sun 10/18	BUF	@	LV	4:25 PM
Sun 11/1	BAL	@	BUF	1:00 PM

Last Game

Lions

1 - 1

Final

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2 - 0

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Young

627

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Rec TD Leaders

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Opp PPG Rankings

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Total Yards Rankings

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Rush Yards Rankings

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NFL Fantasy 2026

Fantasy RB Rankings

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Fantasy WR Rankings

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NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	0	0	1.000
Giants	1	1	0	.500
Cowboys	1	1	0	.500
Commanders	0	2	0	.000
NFC North	W	L	T	PCT
Vikings	2	0	0	1.000
Lions	1	1	0	.500
Bears	1	1	0	.500
Packers	1	1	0	.500
NFC South	W	L	T	PCT
Panthers	1	1	0	.500
Saints	1	1	0	.500
Buccaneers	0	2	0	.000
Falcons	0	2	0	.000
NFC West	W	L	T	PCT
Seahawks	2	0	0	1.000
49ers	2	0	0	1.000
Rams	1	1	0	.500
Cardinals	1	1	0	.500

AFC East	W	L	T	PCT
Bills	2	0	0	1.000
Patriots	1	1	0	.500
Jets	1	1	0	.500
Dolphins	0	2	0	.000
AFC North	W	L	T	PCT
Bengals	2	0	0	1.000
Ravens	1	1	0	.500
Steelers	1	1	0	.500
Browns	1	1	0	.500
AFC South	W	L	T	PCT
Jaguars	1	1	0	.500
Titans	0	2	0	.000
Texans	0	2	0	.000
Colts	0	2	0	.000
AFC West	W	L	T	PCT
Chiefs	2	0	0	1.000
Raiders	2	0	0	1.000
Broncos	1	1	0	.500
Chargers	0	2	0	.000

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DATE	MATCHUP			SCORE
Wed 9/9	NE	@	SEA	10-13
Thu 9/10	SF	@	LAR	27-7
Sun 9/13	CHI	@	CAR	59-37
Sun 9/13	BAL	@	IND	41-23
Sun 9/13	ATL	@	PIT	13-20

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DATE	MATCHUP			TIME (ET)
Thu 9/24	ATL	@	GB	8:15 PM
Sun 9/27	KC	@	MIA	1:00 PM
Sun 9/27	CAR	@	CLE	1:00 PM
Sun 9/27	TEN	@	NYG	1:00 PM
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O.J. Simpson rushed for his most yards in a game against the Lions on November 25, 1976, with 273 yards.

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