Interpreted as:
defensive sack leader 2022| NAME | SEASON | TM | GP | SCK | TKL | AST | COMB | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Nick Bosa | 2022 |  SF | 16 | 18.5 | 41 | 9 | 50 | 137.5 | 0 | 0 | 0 | 2 | 0 | 0 |
 | Myles Garrett | 2022 |  CLE | 16 | 16.0 | 37 | 23 | 60 | 91 | 0 | 0 | 0 | 2 | 0 | 0 |
 | Haason Reddick | 2022 |  PHI | 17 | 16.0 | 35 | 14 | 49 | 132.5 | 0 | 0 | 0 | 5 | 3 | 0 |
| Chris Jones | 2022 |  KC | 17 | 15.5 | 30 | 14 | 44 | 105.5 | 0 | 0 | 0 | 2 | 1 | 0 |
 | Matt Judon | 2022 |  NE | 17 | 15.5 | 36 | 24 | 60 | 102.5 | 0 | 0 | 0 | 2 | 1 | 0 |
| Alex Highsmith | 2022 |  PIT | 17 | 14.5 | 38 | 25 | 63 | 118 | 0 | 0 | 0 | 5 | 0 | 0 |
 | Micah Parsons | 2022 |  DAL | 17 | 13.5 | 42 | 23 | 65 | 88.5 | 0 | 0 | 0 | 3 | 3 | 1 |
 | J.J. Watt | 2022 |  ARI | 16 | 12.5 | 30 | 9 | 39 | 94 | 0 | 0 | 0 | 1 | 1 | 0 |
| Maxx Crosby | 2022 |  LV | 17 | 12.5 | 58 | 31 | 89 | 102 | 0 | 0 | 0 | 3 | 1 | 0 |
| Brian Burns | 2022 |  CAR | 16 | 12.5 | 34 | 29 | 63 | 83 | 0 | 0 | 0 | 1 | 0 | 0 |
| Quinnen Williams | 2022 |  NYJ | 16 | 12.0 | 35 | 20 | 55 | 98.5 | 0 | 0 | 0 | 2 | 1 | 0 |
| Daron Payne | 2022 |  WAS | 17 | 11.5 | 32 | 32 | 64 | 81.5 | 0 | 0 | 0 | 0 | 1 | 0 |
| Josh Uche | 2022 | NE | 15 | 11.5 | 23 | 4 | 27 | 49.5 | 0 | 0 | 0 | 2 | 0 | 0 |
| Brandon Graham | 2022 | PHI | 17 | 11.0 | 19 | 16 | 35 | 64 | 0 | 0 | 0 | 2 | 0 | 0 |
| Javon Hargrave | 2022 | PHI | 17 | 11.0 | 37 | 23 | 60 | 75 | 0 | 0 | 0 | 1 | 2 | 0 |
| Josh Sweat | 2022 | PHI | 16 | 11.0 | 31 | 17 | 48 | 84 | 1 | 42 | 1 | 1 | 0 | 0 |
| Cameron Heyward | 2022 | PIT | 17 | 10.5 | 39 | 35 | 74 | 72.5 | 0 | 0 | 0 | 1 | 1 | 0 |
| Danielle Hunter | 2022 |  MIN | 17 | 10.5 | 46 | 19 | 65 | 63 | 0 | 0 | 0 | 1 | 0 | 0 |
| Za'Darius Smith | 2022 | MIN | 16 | 10.0 | 32 | 12 | 44 | 70.5 | 0 | 0 | 0 | 1 | 0 | 0 |
 | Justin Houston | 2022 |  BAL | 14 | 9.5 | 14 | 7 | 21 | 63 | 1 | 5 | 0 | 1 | 0 | 0 |
| Yannick Ngakoue | 2022 |  IND | 15 | 9.5 | 18 | 11 | 29 | 62.5 | 0 | 0 | 0 | 1 | 0 | 0 |
| Uchenna Nwosu | 2022 |  SEA | 17 | 9.5 | 42 | 24 | 66 | 62.5 | 0 | 0 | 0 | 3 | 2 | 0 |
| Darrell Taylor | 2022 | SEA | 16 | 9.5 | 22 | 4 | 26 | 73.5 | 0 | 0 | 0 | 4 | 1 | 0 |
| Aidan Hutchinson | 2022 |  DET | 17 | 9.5 | 34 | 18 | 52 | 59.5 | 3 | 25 | 0 | 0 | 2 | 0 |
| Jerry Hughes | 2022 |  HOU | 17 | 9.0 | 21 | 14 | 35 | 61 | 1 | 14 | 0 | 2 | 0 | 0 |
StatMuse has season-level data for sacks going back to the 1982 season.