Chris Chambers has the most receiving yards in a game versus the Bills, with 238 yards on December 4, 2005.

what is the most receiving yards against the bills in a game by one player regular season or playoffs
12/4/2005Chambers10/29/1961Hennigan9/25/2011Welker10/9/1983Duper11/27/1960Taylor10/8/2017Green11/26/1964Alworth12/5/1993Brown9/3/1995Sharpe12/19/1965Maynard10/26/2008Ginn12/10/1961Kocourek1/24/2021Hill9/19/1965Taylor9/15/1963Daniels11/12/1967Sauer11/24/1994Moore9/23/2001Pathon10/10/1965Alworth9/29/2013Smith11/24/1968Little11/8/1964Turner238232217202199189185183180180175175172172172170169168168166165165
NAMEDATEGAME TYPETMOPPREC YDSRECTRGREC AVGREC TDRUSH YDSATTRUSH AVGRUSH TD
Chris ChambersChris Chambers12/4/2005REGMIAMIAvs. BUF
vs.
238152615.91000
Charley HenniganCharley Hennigan10/29/1961REGHOUHOU@ BUF
@
232925.82000
Wes WelkerWes Welker9/25/2011REGNENE@ BUF
@
217162013.6219119.00
Mark DuperMark Duper10/9/1983REGMIAMIAvs. BUF
vs.
202728.92000
Lionel TaylorLionel Taylor11/27/1960REGDENDENvs. BUF
vs.
199922.13000
A.J. GreenA.J. Green10/8/2017REGCINCINvs. BUF
vs.
18971327.01000
Lance AlworthLance Alworth11/26/1964REGSDSDvs. BUF
vs.
185446.32000
Tim BrownTim Brown12/5/1993REGRAIRAI@ BUF
@
1831018.31000
Shannon SharpeShannon Sharpe9/3/1995REGDENDENvs. BUF
vs.
1801018.00000
Don MaynardDon Maynard12/19/1965REGNYJNYJvs. BUF
vs.
180920.02000
Ted GinnTed Ginn10/26/2008REGMIAMIAvs. BUF
vs.
1757925.00000
Dave KocourekDave Kocourek12/10/1961REGSDSDvs. BUF
vs.
175358.31000
Tyreek HillTyreek Hill1/24/2021PSTKCKCvs. BUF
vs.
17291119.10000
Lionel TaylorLionel Taylor9/19/1965REGDENDENvs. BUF
vs.
172919.11000
Clem DanielsClem Daniels9/15/1963REGOAKOAKvs. BUF
vs.
172357.3176135.80
George SauerGeorge Sauer11/12/1967REGNYJNYJvs. BUF
vs.
170628.31000
Herman MooreHerman Moore11/24/1994REGDETDETvs. BUF
vs.
169724.11000
Jerome PathonJerome Pathon9/23/2001REGINDINDvs. BUF
vs.
1689918.71000
Lance AlworthLance Alworth10/10/1965REGSDSD@ BUF
@
168821.02000
Torrey SmithTorrey Smith9/29/2013REGBALBAL@ BUF
@
16651233.21000
Floyd LittleFloyd Little11/24/1968REGDENDENvs. BUF
vs.
165441.3171272.60
Bake TurnerBake Turner11/8/1964REGNYJNYJvs. BUF
vs.
165533.01000
Roy WilliamsRoy Williams10/15/2006REGDETDETvs. BUF
vs.
161101716.11000
Walter MurrayWalter Murray10/4/1987REGINDIND@ BUF
@
161723.02000
Jeremy MaclinJeremy Maclin11/29/2015REGKCKCvs. BUF
vs.
16091117.81000
Results may be incomplete. StatMuse has complete game-level data for receiving yards going back to the 1960 season.

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