Tom Brady had the highest passer rating by a quarterback in a game in 2010, with a 158.3 rating versus the Lions on November 25, 2010.

which quarterback has the highest passer rating in a game in 2010
Interpreted as:
Which quarterback has the highest passer rating in a regular-season game in 2010?
11/25/2010Brady10/31/2010Garrard12/26/2010Palmer11/15/2010Vick12/16/2010Rivers12/6/2010Brady10/3/2010Rivers11/28/2010Cutler1/2/2011Brady9/19/2010Manning12/26/2010Freeman10/24/2010Cassel9/12/2010Young9/26/2010Brady10/18/2010Young11/14/2010Thigpen1/2/2011Roethlisberger11/21/2010Rodgers12/26/2010Rodgers9/12/2010Garrard11/7/2010Rivers9/19/2010Cutler12/5/2010Rodgers158.3157.8157.2150.7150.5148.9148.1146.2145.6145.5144.2144.0142.8142.6142.5141.7141.3141.3139.9138.9137.2136.7135.1
NAMEDATETMOPPRATECMPATTPCTYDSAVGTDTD%INTINT%SCKSCKY
Tom BradyTom Brady11/25/2010NENE@ DET
@
158.3212777.834112.6414.800.013
David GarrardDavid Garrard10/31/2010JAXJAX@ DAL
@
157.8172181.026012.4419.000.0322
Carson PalmerCarson Palmer12/26/2010CINCINvs. SD
vs.
157.2162176.226912.8419.000.000
Michael VickMichael Vick11/15/2010PHIPHI@ WAS
@
150.7202871.433311.9414.300.011
Philip RiversPhilip Rivers12/16/2010SDSDvs. SF
vs.
150.5192576.027310.9312.000.017
Tom BradyTom Brady12/6/2010NENEvs. NYJ
vs.
148.9212972.432611.2413.800.0322
Philip RiversPhilip Rivers10/3/2010SDSDvs. ARI
vs.
148.1152075.024112.1210.000.0110
Jay CutlerJay Cutler11/28/2010CHICHIvs. PHI
vs.
146.2142166.724711.8419.000.0429
Tom BradyTom Brady1/2/2011NENEvs. MIA
vs.
145.6101662.519912.4212.500.000
Peyton ManningPeyton Manning9/19/2010INDINDvs. NYG
vs.
145.5202676.92559.8311.500.015
Josh FreemanJosh Freeman12/26/2010TBTBvs. SEA
vs.
144.2212680.82379.1519.200.0221
Matt CasselMatt Cassel10/24/2010KCKCvs. JAX
vs.
144.0131872.219310.7211.100.013
Vince YoungVince Young9/12/2010TENTENvs. OAK
vs.
142.8131776.51549.1211.800.0214
Tom BradyTom Brady9/26/2010NENEvs. BUF
vs.
142.6212777.82529.3311.100.017
Vince YoungVince Young10/18/2010TENTEN@ JAX
@
142.53560.06112.2120.000.000
Tyler ThigpenTyler Thigpen11/14/2010MIAMIAvs. TEN
vs.
141.74666.76410.7116.700.000
Ben RoethlisbergerBen Roethlisberger1/2/2011PITPIT@ CLE
@
141.3152268.228012.729.100.000
Aaron RodgersAaron Rodgers11/21/2010GBGB@ MIN
@
141.3223171.03019.7412.900.0323
Aaron RodgersAaron Rodgers12/26/2010GBGBvs. NYG
vs.
139.9253767.640410.9410.800.028
David GarrardDavid Garrard9/12/2010JAXJAXvs. DEN
vs.
138.9162176.21708.1314.300.015
Philip RiversPhilip Rivers11/7/2010SDSD@ HOU
@
137.2172373.929512.8417.414.315
Jay CutlerJay Cutler9/19/2010CHICHI@ DAL
@
136.7212972.42779.6310.300.017
Aaron RodgersAaron Rodgers12/5/2010GBGBvs. SF
vs.
135.1213070.02989.9310.000.0424
Josh FreemanJosh Freeman11/14/2010TBTBvs. CAR
vs.
134.2182475.024110.028.300.016
David GarrardDavid Garrard11/14/2010JAXJAXvs. HOU
vs.
134.1243177.434211.026.500.0216

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