Barry Sanders had the most games with 130+ rushing yards, with 42 games.

who has most 130 yard rushing games
Interpreted as:
Who has most 130 or more yard rushing regular-season games?
SandersPaytonDickersonPetersonSmithBrownTomlinsonCampbellMartinSimpsonJohnsonAlexanderBettisPortisGoreTaylorHolmesDavisFaulkHenryMcCoyJohnsonGreen4235333129272624222221212120191918181817171616
NAMEGPRUSH YDSATTYPCRUSH YDS/GRUSH TDREC YDSRECTRGAVGREC YDS/GREC TD
Barry SandersBarry Sanders426,8251,0226.7162.543683867.916.32
Walter PaytonWalter Payton355,6009346.0160.041761819.421.72
Eric DickersonEric Dickerson335,3249175.8161.340424518.312.82
Adrian PetersonAdrian Peterson315,2298236.4168.73844758857.714.42
Emmitt SmithEmmitt Smith294,4947556.0155.0394928485.917.01
Jim BrownJim Brown274,3376286.9160.6357526411.827.97
LaDainian TomlinsonLaDainian Tomlinson264,3996756.5169.2446351121525.724.44
Earl CampbellEarl Campbell243,9397325.4164.134135235.95.60
Curtis MartinCurtis Martin223,4036385.3154.72341755447.619.02
O.J. SimpsonO.J. Simpson223,9315896.7178.724180218.68.20
Chris JohnsonChris Johnson213,2104786.7152.92746862837.522.31
Shaun AlexanderShaun Alexander213,3885745.9161.34323124399.611.04
Jerome BettisJerome Bettis213,0285955.1144.2162252997.810.70
Clinton PortisClinton Portis203,1765535.7158.825448435810.422.42
Frank GoreFrank Gore192,8484636.2149.91137444658.519.71
Fred TaylorFred Taylor192,9814616.5156.92331133449.416.41
Priest HolmesPriest Holmes182,8594716.1158.830604566010.833.65
Terrell DavisTerrell Davis183,0474996.1169.327350408.819.42
Marshall FaulkMarshall Faulk183,0214207.2167.83089595959.449.75
Derrick HenryDerrick Henry172,9934476.7176.13620827347.712.20
LeSean McCoyLeSean McCoy172,6303966.6154.71718137424.910.61
Larry JohnsonLarry Johnson162,5174895.1157.33025834537.616.12
Ahman GreenAhman Green162,5653706.9160.31336753706.922.95
Jamal LewisJamal Lewis162,7524246.5172.01718923318.211.80
Tony DorsettTony Dorsett162,5093427.3156.8163022711.218.91
StatMuse has game-level data for rushing yards going back to the 1960 season.