The Buffalo Bills are 45-42-1 against the spread against the AFC since January 26, 2020.

	TEAM	DATE	ATS	TM			OPP		RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	Bills	9/13/2020	1-0	BUF	-294	vs	NYJ	+235	W 27-17	-6.5	+3.5 (Y)	39.5	+4.5 (O)	3	31	404	254	50.0	100.0
2	Bills	9/20/2020	0-1	BUF	-229	@	MIA	+192	W 31-28	-5.5	-2.5 (N)	42	+17 (O)	4	23	523	410	50.0
3	Bills	10/4/2020	1-0	BUF	-178	@	LV	+148	W 30-23	-3.5	+3.5 (Y)	52.5	+0.5 (O)	4	21	337	383	53.8	100.0
4	Bills	10/13/2020	0-1	BUF	-166	@	TEN	+141	L 16-42	-3	-29 (N)	52	+6 (O)	2	23	370	334	76.5
5	Bills	10/19/2020	0-1	BUF	+204	vs	KC	-246	L 17-26	+5.5	-3.5 (N)	54.5	-11.5 (U)	2	20	206	466	44.4
6	Bills	10/25/2020	0-1	BUF	-415	@	NYJ	+330	W 18-10	-9.5	-1.5 (N)	46.5	-18.5 (U)	0	26	422	191	27.3
7	Bills	11/1/2020	0-1	BUF	-206	vs	NE	+172	W 24-21	-4	-1 (N)	41	+4 (O)	3	22	339	349	45.5
8	Bills	11/29/2020	1-0	BUF	-217	vs	LAC	+180	W 27-17	-4	+6 (Y)	51	-7 (U)	3	23	332	367	44.4
9	Bills	12/13/2020	1-0	BUF	-132	vs	PIT	+112	W 26-15	-2	+9 (Y)	48.5	-7.5 (U)	3	21	334	224	50.0
10	Bills	12/19/2020	1-0	BUF	-249	@	DEN	+209	W 48-19	-6	+23 (Y)	48.5	+18.5 (O)	6	29	534	255	69.2	0.0
11	Bills	12/28/2020	1-0	BUF	-349	@	NE	+275	W 38-9	-7	+22 (Y)	47	0 (P)	5	31	474	201	41.7	100.0
12	Bills	1/3/2021	1-0	BUF	+144	vs	MIA	-171	W 56-26	+3.5	+33.5 (Y)	43	+39 (O)	8	24	455	454	40.0
13	Bills	1/9/2021	0-1	BUF	-347	vs	IND	+278	W 27-24	-7	-4 (N)	51	0 (P)	3	22	397	472	22.2
14	Bills	1/16/2021	1-0	BUF	-139	vs	BAL	+117	W 17-3	-2.5	+11.5 (Y)	50	-30 (U)	2	17	220	340	30.8
15	Bills	1/24/2021	0-1	BUF	+135	@	KC	-162	L 24-38	+3	-11 (N)	55	+7 (O)	2	24	363	439	35.7	100.0
16	Bills	9/12/2021	0-1	BUF	-286	vs	PIT	+229	L 16-23	-6.5	-13.5 (N)	48.5	-9.5 (U)	1	22	371	252	44.4	33.3
17	Bills	9/19/2021	1-0	BUF	-188	@	MIA	+159	W 35-0	-3.5	+31.5 (Y)	48	-13 (U)	5	21	314	216	53.8	100.0
18	Bills	10/3/2021	1-0	BUF	-1784	vs	HOU	+957	W 40-0	-19	+21 (Y)	47.5	-7.5 (U)	4	26	450	109	41.7	50.0
19	Bills	10/10/2021	1-0	BUF	+124	@	KC	-146	W 38-20	+3	+21 (Y)	56.5	+1.5 (O)	5	20	436	392	45.5
20	Bills	10/18/2021	0-1	BUF	-270	@	TEN	+218	L 31-34	-6	-9 (N)	53.5	+11.5 (O)	3	28	417	362	53.8	0.0
21	Bills	10/31/2021	0-0-1	BUF	-1046	vs	MIA	+681	W 26-11	-15	0 (P)	48.5	-11.5 (U)	3	24	351	262	46.2	0.0
22	Bills	11/7/2021	0-1	BUF	-1144	@	JAX	+704	L 6-9	-14.5	-17.5 (N)	48.5	-33.5 (U)	0	17	301	218	40.0	0.0
23	Bills	11/14/2021	1-0	BUF	-777	@	NYJ	+533	W 45-17	-13.5	+14.5 (Y)	48.5	+13.5 (O)	6	26	489	366	57.1
24	Bills	11/21/2021	0-1	BUF	-310	vs	IND	+244	L 15-41	-7	-33 (N)	49.5	+6.5 (O)	2	19	311	370	50.0
25	Bills	12/6/2021	0-1	BUF	-147	vs	NE	+124	L 10-14	-3	-7 (N)	40	-16 (U)	1	16	230	241	30.8	0.0
	Average		0.6											3.3	22.4	372.9	319.2	46.4	0.0
	Total		45-42-1											292	1,967	32,819	28,089	46.4	64.7

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StatMuse has team, game-level data for spread records going back to the 1979 season.

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More Bills Stats

Team Leaders

PASS

1,039

Allen

RUSH

421

Cook

REC

270

Kincaid

Team Rankings

PPG

31.8

1st

OPP PPG

26.8

25th

RUSH YDS/G

139.0

5th

PASS YDS/G

259.8

9th

2026 Division Standings

TEAM	W	L	PCT
Bills	3	1	.750
Patriots	2	2	.500
Jets	1	3	.250
Dolphins	0	4	.000

Schedule

DATE	MATCHUP			TIME (ET)
Mon 10/12	BUF	@	LAR	8:15 PM
Sun 10/18	BUF	@	LV	4:25 PM
Sun 11/1	BAL	@	BUF	1:00 PM
Mon 11/9	BUF	@	MIN	8:15 PM
Sun 11/15	BUF	@	NYJ	1:00 PM

Last Game

Patriots

2 - 2

Final

Bills

3 - 1

Sun 4 Oct 2026

NFL 2026 Leaders

Pass Yards Leaders

1,268

Young

1,214

Goff

1,189

Stafford

Rush Yards Leaders

537

Walker

421

Cook

374

Henry

Rec Yards Leaders

498

Lamb

481

Smith-Njigba

401

Higgins

Pass TD Leaders

11

Purdy

11

Cousins

9

Young

Rush TD Leaders

7

Allen

7

Henry

6

Taylor

Rec TD Leaders

6

Smith-Njigba

5

St. Brown

4

Watson

QB Rating Leaders

126.2

Purdy

119.6

Jackson

111.2

Lawrence

Sack Leaders

6.0

Rousseau

5.5

Turner

4.5

Anderson

NFL 2026 Rankings

PPG Rankings

31.8

30.5

30.3

29.8

29.5

Opp PPG Rankings

12.8

13.3

16.0

16.3

18.3

19.3

Total Yards Rankings

429.0

417.0

412.0

405.8

395.0

389.3

Rush Yards Rankings

196.3

173.0

162.3

153.5

139.0

137.3

Pass Yards Rankings

317.0

305.7

303.5

300.5

292.8

285.3

Sack Leaders

16.0

15.0

14.0

12.0

NFL Fantasy 2026

Fantasy RB Rankings

98.1

Walker

94

Gibbs

83.8

Henry

Fantasy WR Rankings

84.7

Smith-Njigba

75.2

Lamb

60.3

St. Brown

Fantasy TE Rankings

48.4

Kittle

36.6

Kelce

36.2

McBride

Fantasy K Rankings

54

Shrader

52

Reichard

47

McPherson

NFL 2026 Betting

Best Record ATS

4-0

3-1

Worst Record ATS

0-4

0-3-1

1-3

NFL 2026 Standings

NFC East	W	L	T	PCT
Giants	3	1	0	.750
Eagles	2	2	0	.500
Cowboys	2	2	0	.500
Commanders	1	3	0	.250
NFC North	W	L	T	PCT
Vikings	4	0	0	1.000
Bears	3	1	0	.750
Lions	2	2	0	.500
Packers	2	2	0	.500
NFC South	W	L	T	PCT
Panthers	2	2	0	.500
Saints	1	2	0	.333
Falcons	1	2	0	.333
Buccaneers	0	4	0	.000
NFC West	W	L	T	PCT
49ers	4	0	0	1.000
Seahawks	3	1	0	.750
Rams	2	2	0	.500
Cardinals	1	3	0	.250

AFC East	W	L	T	PCT
Bills	3	1	0	.750
Patriots	2	2	0	.500
Jets	1	3	0	.250
Dolphins	0	4	0	.000
AFC North	W	L	T	PCT
Browns	3	1	0	.750
Ravens	3	1	0	.750
Steelers	2	2	0	.500
Bengals	2	2	0	.500
AFC South	W	L	T	PCT
Jaguars	3	1	0	.750
Colts	2	2	0	.500
Titans	0	4	0	.000
Texans	0	4	0	.000
AFC West	W	L	T	PCT
Chiefs	4	0	0	1.000
Raiders	3	1	0	.750
Broncos	2	2	0	.500
Chargers	0	4	0	.000

NFL 2026 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Wed 9/9	NE	@	SEA	10-13
Thu 9/10	SF	@	LAR	27-7
Sun 9/13	CHI	@	CAR	59-37
Sun 9/13	BAL	@	IND	41-23
Sun 9/13	ATL	@	PIT	13-20

Schedule

DATE	MATCHUP			TIME (ET)
Mon 10/5	ATL	@	NO	8:15 PM
Thu 10/8	TB	@	DAL	8:15 PM
Sun 10/11	PHI	@	JAX	9:30 AM
Sun 10/11	CLE	@	NYJ	1:00 PM
Sun 10/11	CIN	@	MIA	1:00 PM

The Buffalo Bills are 45-42-1 against the spread against the AFC since January 26, 2020.

Related Searches

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More Bills Stats

1,039

421

270

NFL 2026 Leaders

1,268

1,214

1,189

537

421

374

498

481

401

11

11

9

7

7

6

6

5

4

126.2

119.6

111.2

6.0

5.5

4.5

NFL 2026 Rankings

NFL Fantasy 2026

98.1

94

83.8

84.7

75.2

60.3

48.4

36.6

36.2

54

52

47

NFL 2026 Betting

NFL 2026 Standings

NFL 2026 Scores & Schedule

Scores

Schedule