The Arizona Cardinals have a 7-4 record against the spread against the NFC South since January 22, 2021.
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| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 11/14/2021 | 0-1 | -317 | vs | +251 | L 10-34 | -7 | -31 (N) | 41.5 | +2.5 (O) | 1 | 11 | 169 | 341 | 30.8 | 0.0 | ||
| 2 | | Cardinals | 10/2/2022 | 1-0 | -104 | @ | -116 | W 26-16 | +1 | +11 (Y) | 44 | -2 (U) | 3 | 20 | 338 | 220 | 40.0 | 0.0 | ||
| 3 | | Cardinals | 10/20/2022 | 1-0 | -144 | vs | +121 | W 42-34 | -2.5 | +5.5 (Y) | 43.5 | +32.5 (O) | 5 | 21 | 326 | 494 | 30.0 | 100.0 | ||
| 4 | | Cardinals | 12/25/2022 | 1-0 | +285 | vs | -364 | L 16-19 | +7.5 | +4.5 (Y) | 41.5 | -6.5 (U) | 1 | 16 | 325 | 396 | 26.3 | 100.0 | ||
| 5 | | Cardinals | 1/1/2023 | 1-0 | +236 | @ | -293 | L 19-20 | +6.5 | +5.5 (Y) | 40.5 | -1.5 (U) | 1 | 22 | 339 | 298 | 36.4 | 0.0 | ||
| 6 | | Cardinals | 11/12/2023 | 1-0 | +110 | vs | -131 | W 25-23 | +2 | +4 (Y) | 43.5 | +4.5 (O) | 2 | 20 | 352 | 254 | 27.3 | 100.0 | ||
| 7 | | Cardinals | 12/22/2024 | 0-1 | -251 | @ | +205 | L 30-36 | -5.5 | -11.5 (N) | 47 | +19 (O) | 3 | 23 | 382 | 392 | 46.2 | 100.0 | ||
| 8 | | Cardinals | 9/7/2025 | 1-0 | -267 | @ | +218 | W 20-13 | -6.5 | +0.5 (Y) | 44.5 | -11.5 (U) | 2 | 19 | 276 | 315 | 46.2 | |||
| 9 | | Cardinals | 9/14/2025 | 0-1 | -325 | vs | +262 | W 27-22 | -7 | -2 (N) | 45.5 | +3.5 (O) | 3 | 16 | 293 | 352 | 33.3 | 100.0 | ||
| 10 | | Cardinals | 11/30/2025 | 1-0 | +181 | @ | -221 | L 17-20 | +4.5 | +1.5 (Y) | 45.5 | -8.5 (U) | 2 | 22 | 386 | 279 | 37.5 | 0.0 | ||
| 11 | | Cardinals | 12/21/2025 | 0-1 | +123 | vs | -150 | L 19-26 | +2.5 | -4.5 (N) | 48.5 | -3.5 (U) | 1 | 16 | 320 | 342 | 53.8 | |||
| Average | 5.8 | 2.2 | 18.7 | 318.7 | 334.8 | 37.0 | 0.0 | |||||||||||||
| Total | 7-4 | 24 | 206 | 3,506 | 3,683 | 37.0 | 38.5 |
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More Cardinals Stats
Team Leaders 
PASS
1,600
Brissett
RUSH
245
Love
REC
472
McBride
Team Rankings
PPG
20.3
26th
OPP PPG
29.7
32nd
RUSH YDS/G
96.0
23rd
PASS YDS/G
229.6
21st
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NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 2 | 1 | .643 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
6 | 0 | 0 | 1.000 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| NFC South | W | L | T | PCT |
3 | 3 | 0 | .500 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
| NFC West | W | L | T | PCT |
6 | 1 | 0 | .857 | |
4 | 3 | 0 | .571 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 |
Giants
Eagles
Vikings
Bears
Lions
Packers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 3 | 0 | .571 | |
2 | 5 | 0 | .286 | |
1 | 5 | 0 | .167 | |
| AFC North | W | L | T | PCT |
5 | 2 | 0 | .714 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
1 | 6 | 0 | .143 | |
| AFC West | W | L | T | PCT |
5 | 1 | 0 | .833 | |
5 | 2 | 0 | .714 | |
3 | 4 | 0 | .429 | |
0 | 6 | 0 | .000 |
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