The Arizona Cardinals have a record of 74-107 against the AFC in the regular-season and playoffs since November 6, 1976.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 12/4/1976 | 1-0 |  STL | vs |  BAL | W 24-17 | 1.000 | 3 | 20 | 375 | 279 | ||
| 2 | | Cardinals | 9/18/1977 | 0-1 | STL | @ |  DEN | L 0-7 | .000 | 0 | 12 | 273 | 258 | ||
| 3 | | Cardinals | 11/24/1977 | 0-1 | STL | vs |  MIA | L 14-55 | .000 | 2 | 13 | 210 | 503 | ||
| 4 | | Cardinals | 9/10/1978 | 0-1 | STL | vs |  NE | L 6-16 | .000 | 1 | 9 | 193 | 441 | ||
| 5 | | Cardinals | 10/1/1978 | 0-1 | STL | @ | MIA | L 10-24 | .000 | 1 | 19 | 351 | 267 | ||
| 6 | | Cardinals | 10/8/1978 | 0-1 | STL | vs | BAL | L 17-30 | .000 | 2 | 21 | 343 | 222 | ||
| 7 | | Cardinals | 10/22/1978 | 0-1 | STL | @ |  NYJ | L 10-23 | .000 | 1 | 13 | 304 | 293 | ||
| 8 | | Cardinals | 9/16/1979 | 0-1 | STL | vs |  PIT | L 21-24 | .000 | 2 | 12 | 212 | 398 | ||
| 9 | | Cardinals | 10/7/1979 | 1-0 | STL | @ |  HOU | W 24-17 | 1.000 | 3 | 26 | 447 | 222 | ||
| 10 | | Cardinals | 10/28/1979 | 0-1 | STL | vs |  CLE | L 20-38 | .000 | 3 | 16 | 282 | 418 | ||
| 11 | | Cardinals | 11/25/1979 | 0-1 | STL | @ |  CIN | L 28-34 | .000 | 4 | 26 | 480 | 342 | ||
| 12 | | Cardinals | 10/26/1980 | 1-0 | STL | @ | BAL | W 17-10 | 1.000 | 2 | 13 | 266 | 225 | ||
| 13 | | Cardinals | 11/23/1980 | 0-1 | STL | vs |  KC | L 13-21 | .000 | 1 | 16 | 319 | 321 | ||
| 14 | | Cardinals | 9/6/1981 | 0-1 | STL | vs | MIA | L 7-20 | .000 | 1 | 14 | 203 | 292 | ||
| 15 | | Cardinals | 11/15/1981 | 1-0 | STL | vs |  BUF | W 24-0 | 1.000 | 3 | 22 | 338 | 311 | ||
| 16 | | Cardinals | 11/22/1981 | 1-0 | STL | @ | BAL | W 35-24 | 1.000 | 5 | 24 | 452 | 385 | ||
| 17 | | Cardinals | 11/29/1981 | 1-0 | STL | @ | NE | W 27-20 | 1.000 | 3 | 25 | 412 | 353 | ||
| 18 | | Cardinals | 10/2/1983 | 0-1 | STL | @ | KC | L 14-38 | .000 | 2 | 10 | 194 | 289 | ||
| 19 | | Cardinals | 11/13/1983 | 1-0 | STL | vs |  SEA | W 33-28 | 1.000 | 4 | 22 | 408 | 249 | ||
| 20 | | Cardinals | 11/20/1983 | 1-0 | STL | vs |  SD | W 44-14 | 1.000 | 6 | 18 | 378 | 315 | ||
| 21 | | Cardinals | 12/11/1983 | 1-0 | STL | @ |  RAI | W 34-24 | 1.000 | 5 | 26 | 366 | 327 | ||
| 22 | | Cardinals | 9/9/1984 | 1-0 | STL | vs | BUF | W 37-7 | 1.000 | 4 | 28 | 486 | 171 | ||
| 23 | | Cardinals | 9/16/1984 | 1-0 | STL | @ |  IND | W 34-33 | 1.000 | 4 | 19 | 397 | 399 | ||
| 24 | | Cardinals | 9/30/1984 | 0-1 | STL | vs | MIA | L 28-36 | .000 | 4 | 24 | 445 | 552 | ||
| 25 | | Cardinals | 12/2/1984 | 1-0 | STL | @ | NE | W 33-10 | 1.000 | 4 | 20 | 305 | 223 | ||
| Average | .409 | 2.4 | 18.7 | 318.7 | 334.7 | ||||||||||
| Total | 74-107 | .409 | 430 | 3,385 | 57,682 | 60,586 | |||||||||
More Cardinals Stats
Team Rankings
PPG
21.7
20th
OPP PPG
21.2
13th
RUSH YDS/G
113.2
17th
PASS YDS/G
213.7
20th
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NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 2 | 0 | .667 |
 Commanders | 3 | 2 | 0 | .600 |
| NFC North | W | L | T | PCT |
 Packers | 3 | 1 | 1 | .700 |
 Lions | 4 | 2 | 0 | .667 |
| NFC South | W | L | T | PCT |
 Buccaneers | 5 | 1 | 0 | .833 |
 Panthers | 3 | 3 | 0 | .500 |
| NFC West | W | L | T | PCT |
 49ers | 4 | 2 | 0 | .667 |
| Seahawks | 4 | 2 | 0 | .667 |
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