The San Francisco 49ers made their most tackles in a game against the St. Louis Rams on November 11, 2012, with 72 tackles.
Interpreted as:
most tackles in a regular-season game 49ers all-time| TEAM | TKL | DATE | TM | OPP | RESULT | AST | COMB | SCK | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 72 | 11/11/2012 |  SF | vs |  STL | T 24-24 | 10 | 82 | 2.0 | 16 | 0 | 0 | 0 | 2 | 1 | 0 |
| 2 | | 49ers | 70 | 12/21/2008 | SF | @ | STL | W 17-16 | 2 | 72 | 3.0 | 19 | 1 | 0 | 0 | 0 | 0 | 0 |
| 3 | | 49ers | 70 | 11/25/2007 | SF | @ |  ARI | W 37-31 | 12 | 82 | 4.0 | 30 | 2 | 0 | 0 | 3 | 2 | 1 |
| 4 | | 49ers | 69 | 12/6/2009 | SF | @ |  SEA | L 17-20 | 17 | 86 | 5.0 | 20 | 0 | 0 | 0 | 3 | 1 | 0 |
| 5 | | 49ers | 69 | 11/25/2001 | SF | @ |  IND | W 40-21 | 18 | 87 | 1.0 | 6 | 4 | 76 | 1 | 2 | 1 | 0 |
| 6 | | 49ers | 68 | 12/11/2016 | SF | vs |  NYJ | L 17-23 | 12 | 80 | 6.0 | 41 | 1 | 8 | 0 | 0 | 0 | 0 |
| 7 | | 49ers | 67 | 11/6/2016 | SF | vs |  NO | L 23-41 | 13 | 80 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | 49ers | 67 | 11/1/2009 | SF | @ | IND | L 14-18 | 17 | 84 | 3.0 | 20 | 0 | 0 | 0 | 2 | 0 | 0 |
| 9 | | 49ers | 67 | 10/28/2001 | SF | @ |  CHI | L 31-37 | 4 | 71 | 0.0 | 0 | 2 | 97 | 1 | 1 | 1 | 1 |
| 10 | | 49ers | 65 | 12/26/2010 | SF | @ | STL | L 17-25 | 6 | 71 | 1.0 | 17 | 0 | 0 | 0 | 2 | 1 | 0 |
| 11 | | 49ers | 65 | 12/11/2005 | SF | @ | SEA | L 3-41 | 19 | 84 | 1.0 | 6 | 1 | 0 | 0 | 1 | 0 | 0 |
| 12 | | 49ers | 65 | 10/2/2005 | SF | @ | ARI | L 14-31 | 16 | 81 | 3.0 | 19 | 0 | 0 | 0 | 3 | 3 | 2 |
| 13 | | 49ers | 64 | 10/11/2015 | SF | @ |  NYG | L 27-30 | 28 | 92 | 0.0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| 14 | | 49ers | 64 | 11/22/2009 | SF | @ |  GB | L 24-30 | 14 | 78 | 2.0 | 18 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15 | | 49ers | 64 | 9/30/2007 | SF | vs | SEA | L 3-23 | 10 | 74 | 2.0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 |
| 16 | | 49ers | 64 | 12/9/2001 | SF | @ | STL | L 14-27 | 10 | 74 | 4.0 | 24 | 1 | 20 | 0 | 1 | 1 | 0 |
| 17 | | 49ers | 63 | 10/23/2016 | SF | vs |  TB | L 17-34 | 17 | 80 | 2.0 | 5 | 1 | 21 | 0 | 0 | 0 | 0 |
| 18 | | 49ers | 63 | 10/3/2010 | SF | @ |  ATL | L 14-16 | 10 | 73 | 3.0 | 14 | 2 | 39 | 0 | 0 | 0 | 0 |
| 19 | | 49ers | 63 | 12/2/2007 | SF | @ |  CAR | L 14-31 | 8 | 71 | 2.0 | 12 | 2 | 0 | 0 | 0 | 0 | 0 |
| 20 | | 49ers | 63 | 11/17/2002 | SF | @ |  SD | L 17-20 | 11 | 74 | 0.0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
| 21 | | 49ers | 62 | 10/22/2015 | SF | vs | SEA | L 3-20 | 20 | 82 | 5.0 | 23 | 2 | 0 | 0 | 0 | 0 | 0 |
| 22 | | 49ers | 62 | 10/27/2013 | SF | @ |  JAX | W 42-10 | 1 | 63 | 0.0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
| 23 | | 49ers | 62 | 12/16/2010 | SF | @ | SD | L 7-34 | 12 | 74 | 1.0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | 49ers | 62 | 10/24/2010 | SF | @ | CAR | L 20-23 | 23 | 85 | 1.0 | 5 | 1 | 31 | 1 | 2 | 2 | 0 |
| 25 | | 49ers | 62 | 12/18/2005 | SF | @ | JAX | L 9-10 | 7 | 69 | 2.0 | 14 | 0 | 0 | 0 | 0 | 0 | 0 |
StatMuse has team, game-level data for tackles going back to the 2001 season.
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82.2
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