Brett Favre has the most career turnovers in the regular season when he has had more than 0 (21/22), with 363 turnovers.

Interpreted as:

most turnovers in 21/22 by a player regular season

	NAME	TOV	21/22	LOST	INT	GP	YDS	YDS/G	TD	RUSH YDS	RUSH YDS/G	RUSH TD	REC YDS	REC YDS/G	REC TD	KR YDS	KR YDS/G	KR TD	PR YDS	PR YDS/G	PR TD
1	Brett Favre B. Favre	363	0.95		336	302	1,654	5.5	14	1,844	6.1	14	-7	0.0	0	0	0.0	0	0	0.0	0
2	Eli Manning E. Manning	300	0.95	56	244	236	510	2.2	7	567	2.4	7	0	0.0	0	0	0.0	0	0	0.0	0
3	Drew Brees D. Brees	285	0.95		243	287	724	2.5	26	752	2.6	25	74	0.3	1	0	0.0	0	0	0.0	0
4	Vinny Testaverde V. Testaverde	278	0.95		267	233	1,580	6.8	15	1,661	7.1	15	6	0.0	0	0	0.0	0	0	0.0	0
5	Peyton Manning P. Manning	268	0.95		251	266	620	2.3	18	667	2.5	18	-2	0.0	0	0	0.0	0	0	0.0	0
6	Ben Roethlisberger B. Roethlisberger	262	0.95	51	211	249	1,231	4.9	20	1,373	5.5	20	-12	0.0	0	0	0.0	0	0	0.0	0
7	Philip Rivers P. Rivers	260	0.95	48	212	247	453	1.8	3	600	2.4	3	-9	0.0	0	0	0.0	0	0	0.0	0
8	Tom Brady T. Brady	260	0.95		212	335	1,060	3.2	28	1,123	3.4	28	65	0.2	0	0	0.0	0	0	0.0	0
9	Matthew Stafford M. Stafford	240	0.95	43	197	240	1,225	5.1	15	1,356	5.7	15	-3	0.0	0	0	0.0	0	0	0.0	0
10	Matt Ryan M. Ryan	232	0.95	49	183	234	1,477	6.3	14	1,539	6.6	13	5	0.0	1	0	0.0	0	0	0.0	0
11	Drew Bledsoe D. Bledsoe	230	0.95		206	194	576	3.0	10	764	3.9	10	-9	0.0	0	0	0.0	0	0	0.0	0
12	Carson Palmer C. Palmer	220	0.95	33	187	182	411	2.3	8	474	2.6	8	0	0.0	0	0	0.0	0	0	0.0	0
13	Kerry Collins K. Collins	218	0.95		196	198	454	2.3	10	686	3.5	10	-13	-0.1	0	0	0.0	0	0	0.0	0
14	Joe Flacco J. Flacco	214	0.95	42	172	209	868	4.2	17	925	4.4	17	32	0.2	0	0	0.0	0	0	0.0	0
15	Ryan Fitzpatrick R. Fitzpatrick	199	0.95	30	169	166	2,555	15.4	21	2,625	15.8	21	-3	0.0	0	0	0.0	0	0	0.0	0
16	Jay Cutler J. Cutler	198	0.95	38	160	153	1,564	10.2	9	1,682	11.0	9	0	0.0	0	0	0.0	0	0	0.0	0
17	Jon Kitna J. Kitna	187	0.95		165	141	880	6.2	11	956	6.8	11	9	0.1	0	0	0.0	0	0	0.0	0
18	Andy Dalton A. Dalton	180	0.95	29	151	179	1,437	8.0	23	1,509	8.4	22	11	0.1	1	0	0.0	0	0	0.0	0
19	Matt Hasselbeck M. Hasselbeck	177	0.95		153	209	1,152	5.5	8	1,231	5.9	8	0	0.0	0	0	0.0	0	0	0.0	0
20	Kirk Cousins K. Cousins	173	0.95	42	131	174	842	4.8	20	965	5.5	20	-1	0.0	0	0	0.0	0	0	0.0	0
21	Jake Plummer J. Plummer	168	0.95		161	143	1,813	12.7	17	1,853	13.0	17	4	0.0	0	0	0.0	0	0	0.0	0
22	Aaron Rodgers A. Rodgers	165	0.95	42	123	264	3,546	13.4	36	3,634	13.8	36	-20	-0.1	0	0	0.0	0	0	0.0	0
23	Kurt Warner K. Warner	162	0.95		128	124	186	1.5	3	286	2.3	3	0	0.0	0	0	0.0	0	0	0.0	0
24	Derek Carr D. Carr	151	0.95	39	112	169	835	4.9	7	956	5.7	7	-9	-0.1	0	0	0.0	0	0	0.0	0
25	Russell Wilson R. Wilson	150	0.95	36	114	205	5,514	26.9	32	5,568	27.2	31	21	0.1	1	0	0.0	0	0	0.0	0

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