The New England Patriots have a 41-25 record against the Bills when playing >0 games at home all-time.
| TEAM | DATE | REC | GP | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Patriots | 9/23/1960 | 0-1 | 1 | vs | L 0-13 | .000 | 0 | 18 | 284 | 233 | ||||
| 2 | | Patriots | 10/22/1961 | 1-0 | 1 | vs | W 52-21 | 1.000 | 7 | 18 | 437 | 275 | ||||
| 3 | | Patriots | 11/23/1962 | 1-0 | 1 | vs | W 21-10 | 1.000 | 3 | 15 | 319 | 255 | ||||
| 4 | | Patriots | 12/1/1963 | 1-0 | 1 | vs | W 17-7 | 1.000 | 2 | 10 | 250 | 239 | ||||
| 5 | | Patriots | 12/20/1964 | 0-1 | 1 | vs | L 14-24 | .000 | 2 | 15 | 319 | 380 | ||||
| 6 | | Patriots | 11/7/1965 | 0-1 | 1 | vs | L 7-23 | .000 | 1 | 15 | 264 | 161 | ||||
| 7 | | Patriots | 12/4/1966 | 1-0 | 1 | vs | W 14-3 | 1.000 | 2 | 12 | 226 | 314 | ||||
| 8 | | Patriots | 12/9/1967 | 0-1 | 1 | vs | L 16-44 | .000 | 2 | 9 | 150 | 252 | ||||
| 9 | | Patriots | 10/20/1968 | 1-0 | 1 | vs | W 23-6 | 1.000 | 2 | 11 | 299 | 203 | ||||
| 10 | | Patriots | 11/23/1969 | 1-0 | 1 | vs | W 35-21 | 1.000 | 5 | 16 | 373 | 425 | ||||
| 11 | | Patriots | 11/1/1970 | 0-1 | 1 | vs | L 10-45 | .000 | 1 | 19 | 251 | 364 | ||||
| 12 | | Patriots | 11/14/1971 | 1-0 | 1 | vs | W 38-33 | 1.000 | 5 | 9 | 299 | 217 | ||||
| 13 | | Patriots | 11/19/1972 | 0-1 | 1 | vs | L 24-27 | .000 | 3 | 15 | 298 | 295 | ||||
| 14 | | Patriots | 9/16/1973 | 0-1 | 1 | vs | L 13-31 | .000 | 2 | 17 | 297 | 459 | ||||
| 15 | | Patriots | 11/3/1974 | 0-1 | 1 | vs | L 28-29 | .000 | 4 | 20 | 355 | 327 | ||||
| 16 | | Patriots | 12/14/1975 | 0-1 | 1 | vs | L 14-34 | .000 | 2 | 16 | 271 | 468 | ||||
| 17 | | Patriots | 11/7/1976 | 1-0 | 1 | vs | W 20-10 | 1.000 | 2 | 16 | 303 | 373 | ||||
| 18 | | Patriots | 11/6/1977 | 0-1 | 1 | vs | L 14-24 | .000 | 2 | 14 | 202 | 399 | ||||
| 19 | | Patriots | 12/10/1978 | 1-0 | 1 | vs | W 26-24 | 1.000 | 3 | 24 | 403 | 307 | ||||
| 20 | | Patriots | 11/25/1979 | 0-1 | 1 | vs | L 13-16 | .000 | 1 | 21 | 309 | 281 | ||||
| 21 | | Patriots | 12/14/1980 | 1-0 | 1 | vs | W 24-2 | 1.000 | 3 | 21 | 324 | 161 | ||||
| 22 | | Patriots | 12/13/1981 | 0-1 | 1 | vs | L 10-19 | .000 | 1 | 16 | 204 | 329 | ||||
| 23 | | Patriots | 1/2/1983 | 1-0 | 1 | vs | W 30-19 | 1.000 | 4 | 29 | 418 | 353 | ||||
| 24 | | Patriots | 11/6/1983 | 1-0 | 1 | vs | W 21-7 | 1.000 | 3 | 19 | 450 | 263 | ||||
| 25 | | Patriots | 11/11/1984 | 1-0 | 1 | vs | W 38-10 | 1.000 | 5 | 21 | 278 | 189 | ||||
| Average | 1.0 | .621 | 2.6 | 18.7 | 321.3 | 315.2 | ||||||||||
| Total | 41-25 | 66 | .621 | 172 | 1,231 | 21,204 | 20,803 | |||||||||
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More Patriots Stats
Team Leaders 
PASS
1,784
Maye
RUSH
285
Stevenson
REC
296
Henry
Team Rankings
PPG
22.9
19th
OPP PPG
20.4
9th
RUSH YDS/G
122.0
11th
PASS YDS/G
261.4
9th
Jets
Dolphins
GB
DET
LAC
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 2 | 1 | .643 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
6 | 0 | 0 | 1.000 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| NFC South | W | L | T | PCT |
3 | 3 | 0 | .500 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
| NFC West | W | L | T | PCT |
6 | 1 | 0 | .857 | |
4 | 3 | 0 | .571 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 |
Giants
Cowboys
Eagles
Commanders
Vikings
Bears
Panthers
Falcons
Buccaneers
Saints
49ers
Seahawks
Rams
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 3 | 0 | .571 | |
2 | 5 | 0 | .286 | |
1 | 5 | 0 | .167 | |
| AFC North | W | L | T | PCT |
5 | 2 | 0 | .714 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
1 | 6 | 0 | .143 | |
| AFC West | W | L | T | PCT |
5 | 1 | 0 | .833 | |
5 | 2 | 0 | .714 | |
3 | 4 | 0 | .429 | |
0 | 6 | 0 | .000 |
Browns
Steelers
Bengals
Ravens
Jaguars
Colts
Texans
Titans
Chiefs
Broncos
Raiders