which defensive linemen has sacked the most different quarterbacks all-time

Bruce Smith has the most career sacks by a defensive lineman, with 200 sacks.

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Regular season

	NAME	SCK	GP	TKL	AST	COMB	SCKY	INT	INT YDS	INT TD	FF	FR	FR TD
1	Bruce Smith B. Smith	200.0	279	85	28	113		2	0	0	6	15	1
2	Reggie White R. White	198.0	232					3	79	0		20	2
3	Chris Doleman C. Doleman	147.0	200					6	57	1		21	1
4	Michael Strahan M. Strahan	141.5	216	338	93	431		4	124	2	14	15	1
5	John Randle J. Randle	137.5	219	51	15	66		1	1	0	4	11	1
6	Richard Dent R. Dent	137.5	203					8	89	1		13	1
7	Jared Allen J. Allen	136.0	187	503	145	648	851.5	6	55	1	31	19	1
8	Julius Peppers J. Peppers	134.5	218	487	127	614	813.5	9	192	2	43	17	2
9	Cameron Jordan C. Jordan	132.0	244	495	270	765	870	3	6	1	17	12	0
10	Myles Garrett M. Garrett	125.5	134	293	119	412	827.5	0	0	0	23	6	1
11	Simeon Rice S. Rice	122.0	174	214	38	252		5	48	0	25	8	0
12	Clyde Simmons C. Simmons	121.5	236					3	85	2		14	2
13	Jason Taylor J. Taylor	120.5	185	336	152	488		7	110	3	34	26	5
14	John Abraham J. Abraham	117.5	169	414	87	501	748.5	1	6	0	42	6	1
15	Calais Campbell C. Campbell	117.0	280	674	289	963	813	3	24	0	18	13	3
16	J.J. Watt	114.5	151	449	137	586	808.5	2	99	2	27	17	1
17	Sean Jones S. Jones	113.0	201					1	0	0		13	1
18	Aaron Donald A. Donald	111.0	155	341	205	546	813	0	0	0	24	7	0
19	Dwight Freeney D. Freeney	108.5	173	267	41	308	813	0	0	0	43	3	1
20	Trace Armstrong T. Armstrong	106.0	211	31	9	40		1	0	0	1	15	0
21	Kevin Carter K. Carter	104.5	224	233	133	366		0	0	0	5	14	0
22	Neil Smith N. Smith	104.5	191					4	68	1		12	1
23	Robert Mathis R. Mathis	103.0	151	349	108	457	723.5	0	0	0	47	14	1
24	Jim Jeffcoat J. Jeffcoat	102.5	227					2	91	2		11	2
25	William Fuller W. Fuller	100.5	194					2	9	0		8	1

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StatMuse has season-level data for sacks going back to the 1982 season.

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More Bills Stats

Team Leaders

PASS

582

Allen

RUSH

192

Cook

REC

225

Kincaid

Team Rankings

PPG

38.5

1st

OPP PPG

31.0

28th

RUSH YDS/G

144.5

6th

PASS YDS/G

291.0

4th

2026 Division Standings

TEAM	W	L	PCT
Bills	2	0	1.000
Patriots	1	1	.500
Jets	1	1	.500
Dolphins	0	2	.000

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/27	LAC	@	BUF	1:00 PM
Sun 10/4	NE	@	BUF	1:00 PM
Mon 10/12	BUF	@	LAR	8:15 PM
Sun 10/18	BUF	@	LV	4:25 PM
Sun 11/1	BAL	@	BUF	1:00 PM

Last Game

Lions

1 - 1

Final

Bills

2 - 0

Thu 17 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

844

Love

662

Shough

648

Young

Rush Yards Leaders

349

Robinson

290

Walker

212

Henry

Rec Yards Leaders

284

Watson

277

Smith-Njigba

274

London

Pass TD Leaders

6

Young

6

Love

6

Prescott

Rush TD Leaders

4

Taylor

4

Allen

4

Henry

Rec TD Leaders

4

Smith-Njigba

4

Watson

4

St. Brown

QB Rating Leaders

127.3

Lock

125.9

Dart

125.8

Allen

Sack Leaders

4.0

Rousseau

3.5

Watt

3.0

Hutchinson

NFL 2026 Rankings

PPG Rankings

38.5

35.5

32.0

31.0

Opp PPG Rankings

8.0

8.5

10.0

12.5

13.5

15.0

Total Yards Rankings

457.5

427.5

424.5

409.0

385.5

Rush Yards Rankings

212.5

186.0

173.0

157.0

155.0

144.5

Pass Yards Rankings

331.0

324.0

313.5

291.0

283.0

281.3

Sack Leaders

8.0

7.0

NFL Fantasy 2026

Fantasy RB Rankings

64.7

Robinson

49

Henry

48.9

Walker

Fantasy WR Rankings

52.4

Watson

51.7

Smith-Njigba

44.9

St. Brown

Fantasy TE Rankings

28.5

Kincaid

25.6

McBride

23.2

Kelce

Fantasy K Rankings

31

McPherson

27

McLaughlin

24

Butker

NFL 2026 Betting

Best Record ATS

2-0

Worst Record ATS

0-2

NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	0	0	1.000
Giants	1	1	0	.500
Cowboys	1	1	0	.500
Commanders	0	2	0	.000
NFC North	W	L	T	PCT
Vikings	2	0	0	1.000
Lions	1	1	0	.500
Bears	1	1	0	.500
Packers	1	2	0	.333
NFC South	W	L	T	PCT
Panthers	1	1	0	.500
Saints	1	1	0	.500
Falcons	1	2	0	.333
Buccaneers	0	2	0	.000
NFC West	W	L	T	PCT
Seahawks	2	0	0	1.000
49ers	2	0	0	1.000
Rams	1	1	0	.500
Cardinals	1	1	0	.500

AFC East	W	L	T	PCT
Bills	2	0	0	1.000
Patriots	1	1	0	.500
Jets	1	1	0	.500
Dolphins	0	2	0	.000
AFC North	W	L	T	PCT
Bengals	2	0	0	1.000
Ravens	1	1	0	.500
Steelers	1	1	0	.500
Browns	1	1	0	.500
AFC South	W	L	T	PCT
Jaguars	1	1	0	.500
Titans	0	2	0	.000
Texans	0	2	0	.000
Colts	0	2	0	.000
AFC West	W	L	T	PCT
Chiefs	2	0	0	1.000
Raiders	2	0	0	1.000
Broncos	1	1	0	.500
Chargers	0	2	0	.000

NFL 2026 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Wed 9/9	NE	@	SEA	10-13
Thu 9/10	SF	@	LAR	27-7
Sun 9/13	CHI	@	CAR	59-37
Sun 9/13	BAL	@	IND	41-23
Sun 9/13	ATL	@	PIT	13-20

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/27	KC	@	MIA	1:00 PM
Sun 9/27	CAR	@	CLE	1:00 PM
Sun 9/27	TEN	@	NYG	1:00 PM
Sun 9/27	NE	@	JAX	1:00 PM
Sun 9/27	LAC	@	BUF	1:00 PM

Bruce Smith has the most career sacks by a defensive lineman, with 200 sacks.

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582

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NFL 2026 Leaders

844

662

648

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212

284

277

274

6

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6

4

4

4

4

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127.3

125.9

125.8

4.0

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NFL 2026 Rankings

NFL Fantasy 2026

64.7

49

48.9

52.4

51.7

44.9

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NFL 2026 Betting

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NFL 2026 Scores & Schedule

Scores

Schedule