The 2021-22 roster for the Avalanche included Nathan MacKinnon at center, Andre Burakovsky at left wing, Mikko Rantanen at right wing, Cale Makar at defenseman and Darcy Kuemper at goalie.

	NO.	NAME	POS	HEIGHT	WEIGHT	DOB	AGE	BIRTHPLACE
1	60	Justus Annunen J. Annunen	G	6'4"	210	3/11/2000	21	Kempele, Finland
2	16	Nicolas Aube-Kubel N. Aube-Kubel	RW	5'11"	187	5/10/1996	25	Slave Lake, Canada
3	20	Justin Barron J. Barron	D	6'2"	195	11/15/2001	20	Halifax, Canada
4	95	Andre Burakovsky A. Burakovsky	LW	6'3"	201	2/9/1995	26	Klagenfurt, Austria
5	4	Bowen Byram B. Byram	D	6'1"	190	6/13/2001	20	Cranbrook, Canada
6	11	Andrew Cogliano A. Cogliano	C	5'10"	175	6/14/1987	34	Toronto, Canada
7	37	J.T. Compher	LW	6'0"	190	4/8/1995	26	Northbrook, IL
8	93	Jean-Luc Foudy J. Foudy	C	5'11"	177	5/13/2002	19	Scarborough, Canada
9	39	Pavel Francouz P. Francouz	G	6'0"	179	6/3/1990	31	Plzen, Czech Republic
10	49	Samuel Girard S. Girard	D	5'10"	170	5/12/1998	23	Roberval, Canada
11	79	Jordan Gross J. Gross	D	5'10"	190	5/9/1995	26	Maple Grove, MN
12	43	Darren Helm D. Helm	C	6'0"	192	1/21/1987	35	St. Andrews, Canada
13	31	Jonas Johansson J. Johansson	G	6'5"	219	9/19/1995	26	Gavle, Sweden
14	6	Erik Johnson E. Johnson	D	6'4"	225	3/21/1988	33	Bloomington, MN
15	3	Jack Johnson J. Johnson	D	6'1"	227	1/13/1987	35	Indianapolis, IN
16	17	Tyson Jost T. Jost	C	5'11"	187	3/14/1998	23	St. Albert, Canada
17	91	Nazem Kadri N. Kadri	C	6'0"	192	10/6/1990	31	London, Canada
18	61	Martin Kaut M. Kaut	RW	6'2"	190	10/2/1999	22	Brno, Czech Republic
19	35	Darcy Kuemper D. Kuemper	G	6'5"	215	5/5/1990	31	Saskatoon, Canada
20	92	Gabriel Landeskog G. Landeskog	LW	6'1"	215	11/23/1992	29	Stockholm, Sweden
21	62	Artturi Lehkonen A. Lehkonen	LW	6'0"	176	7/4/1995	26	Piikkio, Finland
22	56	Kurtis MacDermid K. MacDermid	D	6'5"	233	3/25/1994	27	Quebec City, Canada
23	26	Jacob MacDonald J. MacDonald	D	6'0"	204	2/26/1993	28	Portland, OR
24	29	Nathan MacKinnon N. MacKinnon	C	6'0"	200	9/1/1995	26	Halifax, Canada
25	8	Cale Makar C. Makar	D	5'11"	187	10/30/1998	23	Calgary, Canada