The 2022-23 defensemen for the Senators included Matthew Andonovski, Jonathan Aspirot, Xavier Bernard, Jacob Bernard-Docker and Erik Brännström.

	NO.	NAME	POS	HEIGHT	WEIGHT	DOB	AGE	BIRTHPLACE
1		Matthew Andonovski M. Andonovski	D	6'2"	201	3/14/2005	17	Markham, Canada
2	76	Jonathan Aspirot J. Aspirot	D	6'0"	200	5/16/1999	23	Mascouche, Canada
3		Xavier Bernard X. Bernard	D	6'3"	205	1/6/2000	23	Lery, Canada
4	24	Jacob Bernard-Docker J. Bernard-Docker	D	6'0"	181	6/30/2000	22	Canmore, Canada
5	26	Erik Brännström E. Brännström	D	5'10"	185	9/2/1999	23	Eksjo, Sweden
6	72	Thomas Chabot T. Chabot	D	6'2"	195	1/30/1997	26	Sainte-Marie, Canada
7	6	Jakob Chychrun J. Chychrun	D	6'2"	220	3/31/1998	24	Boca Raton, FL
8		Jorian Donovan J. Donovan	D			4/5/2004	18	Calgary, Canada
9	50	Maxence Guenette M. Guenette	D	6'1"	181	4/28/2001	21	L'Ancienne-Lorette, Canada
10		Tomas Hamara T. Hamara	D			3/9/2004	18	Prague, Czech Republic
11	23	Travis Hamonic T. Hamonic	D	6'1"	200	8/16/1990	32	St. Malo, Canada
12	29	Dillon Heatherington D. Heatherington	D	6'4"	220	5/9/1995	27	Calgary, Canada
13	5	Nick Holden N. Holden	D	6'4"	210	5/15/1987	35	St. Albert, Canada
14	43	Tyler Kleven T. Kleven	D	6'4"	200	1/10/2002	21	Fargo, ND
15	32	Jacob Larsson J. Larsson	D	6'2"	190	4/29/1997	25	Ljungby, Sweden
16		Zachary Massicotte Z. Massicotte	D			3/15/2001	21	Shawinigan, Canada
17		Nikolas Matinpalo N. Matinpalo	D	6'3"	207	10/5/1998	24	Espoo, Finland
18		Filip Nordberg F. Nordberg	D	6'4"	207	3/5/2004	18	Stockholm, Sweden
19		Ben Roger B. Roger	D	6'4"	201	11/3/2002	20	Markham, Canada
20		Chandler Romeo C. Romeo	D	6'5"	205	7/16/2003	19	Cambridge, Canada
21	85	Jake Sanderson J. Sanderson	D	6'3"	195	7/8/2002	20	Whitefish, MT
22		Hoyt Stanley H. Stanley	D	6'2"	187	2/4/2005	17	West Vancouver, Canada
23	60	Lassi Thomson L. Thomson	D	6'0"	190	9/24/2000	22	Tampere, Finland
24	22	Nikita Zaitsev N. Zaitsev	D	6'2"	188	10/29/1991	31	Moscow, Russia
25	2	Artem Zub A. Zub	D	6'2"	200	10/3/1995	27	Khabarovsk, Russia