Ryan O'Reilly has 6 goals, 11 assists and a plus-minus of +4 in 17 games versus the Sabres in his career.

	NAME	DATE	TM		OPP	G	A	P	+/-	PIM	PPA	SHG	SHA	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI
1	Ryan O'Reilly R. O'Reilly	1/9/2010	COL	@	BUF	0	0	0	0	0	0	0	0	0		5	11	45.5	0	1	0	0	16:53
2	Ryan O'Reilly R. O'Reilly	1/4/2011	COL	vs	BUF	1	0	1	0	0	0	1	0	1	100.0	16	29	55.2	0	0	3	0	19:29
3	Ryan O'Reilly R. O'Reilly	3/14/2012	COL	@	BUF	0	1	1	0	0	0	0	0	5	0.0	11	24	45.8	1	1	0	1	25:13
4	Ryan O'Reilly R. O'Reilly	10/19/2013	COL	@	BUF	1	1	2	0	0	1	0	0	5	20.0	2	4	50.0	1	0	0	1	19:46
5	Ryan O'Reilly R. O'Reilly	2/1/2014	COL	vs	BUF	0	2	2	+2	0	1	0	0	0		3	6	50.0	0	1	1	0	20:08
6	Ryan O'Reilly R. O'Reilly	12/20/2014	COL	@	BUF	0	1	1	+1	2	0	0	1	1	0.0	9	18	50.0	0	2	0	0	15:48
7	Ryan O'Reilly R. O'Reilly	3/28/2015	COL	vs	BUF	0	1	1	-2	0	0	0	0	1	0.0	6	17	35.3	0	0	1	0	19:29
8	Ryan O'Reilly R. O'Reilly	12/27/2018	STL	vs	BUF	1	0	1	+2	0	0	0	0	4	25.0	11	18	61.1	0	0	0	0	18:28
9	Ryan O'Reilly R. O'Reilly	3/17/2019	STL	@	BUF	0	1	1	0	0	0	0	0	3	0.0	16	21	76.2	1	0	1	0	22:01
10	Ryan O'Reilly R. O'Reilly	12/10/2019	STL	@	BUF	0	0	0	-3	0	0	0	0	0		13	22	59.1	0	1	1	0	21:34
11	Ryan O'Reilly R. O'Reilly	1/9/2020	STL	vs	BUF	0	1	1	0	0	0	0	0	0		15	24	62.5	0	0	3	0	18:49
12	Ryan O'Reilly R. O'Reilly	2/25/2022	STL	vs	BUF	0	1	1	+1	0	0	0	0	2	0.0	10	18	55.6	0	0	1	1	19:03
13	Ryan O'Reilly R. O'Reilly	4/14/2022	STL	@	BUF	0	0	0	-1	0	0	0	0	0		11	18	61.1	0	0	0	0	16:46
14	Ryan O'Reilly R. O'Reilly	11/23/2022	STL	@	BUF	0	0	0	-1	0	0	0	0	1	0.0	9	18	50.0	1	0	0	0	15:50
15	Ryan O'Reilly R. O'Reilly	2/21/2023	TOR	@	BUF	3	1	4	+3	0	0	0	0	5	60.0	8	14	57.1	0	0	0	0	16:38
16	Ryan O'Reilly R. O'Reilly	12/3/2023	NSH	@	BUF	0	0	0	+1	0	0	0	0	5	0.0	13	20	65.0	0	1	0	1	18:45
17	Ryan O'Reilly R. O'Reilly	3/7/2024	NSH	vs	BUF	0	1	1	+1	0	0	0	0	2	0.0	8	14	57.1	0	0	0	1	20:00
	Total					6	11	17	+4	2	2	1	1	35	17.1	166	296	56.1	4	7	11	5	324:40