The Buffalo Sabres have a record of 76-92-35-11 against the Penguins all-time.

	OPP	REC	PTS	GP	W	L	T	OTL	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Penguins	76-92-35-11	198	214	76	92	35	11	.463	2	4	672	701	-29	17.2	79.5	31.15	10.1	30.94	.894
2	Rangers	90-75-25-15	220	205	90	75	25	15	.537	4	5	638	633	5	19.2	80.3	30.00	10.4	31.34	.901
3	Canadiens	136-120-31-13	316	300	136	120	31	13	.527	9	5	871	918	-47	17.2	81.5	28.60	10.2	30.83	.901
4	Blues	52-61-13-4	121	130	52	61	13	4	.465	1	1	392	437	-45	16.7	79.6	29.21	10.3	29.58	.886
5	Flyers	79-96-20-6	184	201	79	96	20	6	.458	3	3	590	648	-58	19.4	81.8	28.13	10.4	31.22	.897
6	Red Wings	72-65-13-11	168	161	72	65	13	11	.522	5	5	533	524	9	20.1	79.4	28.93	11.4	30.68	.894
7	Blackhawks	61-53-13-5	140	132	61	53	13	5	.530	0	2	415	392	23	16.5	84.3	30.58	10.3	28.85	.897
8	Canucks	54-57-19-2	129	132	54	57	19	2	.489	2	0	431	434	-3	17.7	79.6	29.27	11.2	28.81	.886
9	Barons	25-13-8	58	46	25	13	8	0	.630	0	0	191	139	52	42.9	83.3	31.43	13.2	27.00	.888
10	Kings	67-49-18-1	153	135	67	49	18	1	.567	1	1	486	403	83	21.7	81.9	29.77	12.1	30.10	.901
11	Maple Leafs	123-80-18-11	275	232	123	80	18	11	.593	6	4	817	665	152	21.5	84.2	30.94	11.4	30.21	.905
12	Stars	60-57-17-0	137	134	60	57	17	0	.511	2	0	412	401	11	15.5	82.3	29.99	10.3	29.09	.897
13	Bruins	131-141-29-18	309	319	131	141	29	18	.484	6	8	970	1,031	-61	17.8	82.9	28.13	10.8	31.47	.897
14	Flames	57-42-16-4	134	119	57	42	16	4	.563	3	0	401	371	30	19.7	82.1	29.34	11.5	29.55	.894
15	Islanders	91-77-18-7	207	193	91	77	18	7	.536	7	2	558	547	11	19.2	82.3	30.71	9.4	28.59	.901
16	Devils	86-65-17-11	200	179	86	65	17	11	.559	8	5	563	519	44	19.8	81.5	28.93	10.9	29.55	.902
17	Capitals	98-59-15-11	222	183	98	59	15	11	.607	5	7	627	504	123	19.5	81.6	29.49	11.6	29.30	.906
18	Hurricanes	107-81-18-11	243	217	107	81	18	11	.560	3	3	722	647	75	17.2	82.9	29.85	11.1	29.67	.900
19	Avalanche	64-66-20-5	153	155	64	66	20	5	.494	0	3	518	537	-19	21.2	80.4	29.63	11.3	29.53	.883
20	Oilers	32-44-10-1	75	87	32	44	10	1	.431	1	0	270	307	-37	18.0	82.6	30.25	10.3	30.67	.885
21	Coyotes	52-26-7-3	114	88	52	26	7	3	.648	1	2	300	228	72	23.0	82.7	30.94	11.0	29.26	.911
22	Sharks	32-13-4-2	70	51	32	13	4	2	.686	2	0	181	144	37	22.8	85.7	29.98	11.8	31.67	.911
23	Lightning	62-48-5-5	134	120	62	48	5	5	.558	4	2	355	342	13	15.3	82.0	27.78	10.6	29.92	.905
24	Senators	79-61-10-10	178	160	79	61	10	10	.556	9	6	442	420	22	17.3	84.2	29.81	9.3	32.15	.918
25	Panthers	54-53-4-7	119	118	54	53	4	7	.504	3	5	314	318	-4	19.0	84.0	29.48	9.0	31.59	.915