Rob Ray has the most career penalty minutes for the Sabres, with 3,189 minutes in the box.

	NAME	PIM	GP	G	A	P	+/-	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Rob Ray R. Ray	3,189	889	40	50	90	-38	2	1	0	0	4	0	367	10.9	2	4	50.0	225	14	11	42	4:53
2	Mike Foligno M. Foligno	1,448	664	247	264	511	+115	62	61	2	4	42	1	1,450	17.0
3	Larry Playfair L. Playfair	1,392	577	24	76	100	+2	0	2	0	0	2	0	412	5.8
4	Brad May B. May	1,323	425	67	89	156	-10	9	17	0	0	12	1	688	9.7
5	Matthew Barnaby M. Barnaby	1,248	317	47	79	126	+11	4	11	0	0	6	1	448	10.5
6	Lindy Ruff L. Ruff	1,128	608	102	183	285	+3	17	46	2	3	20	0	1,063	9.6
7	Jim Schoenfeld J. Schoenfeld	1,025	584	45	183	228	+230	16	22	0	8	4	0	1,064	4.2
8	Mike Ramsey M. Ramsey	924	911	73	256	329	+166	12	52	2	9	15	1	1,323	5.5
9	Mike Hartman M. Hartman	890	225	34	26	60	-12	5	1	0	0	5	1	296	11.5
10	Jerry Korab J. Korab	870	537	67	216	283	+78	24	78	3	5	8	0	1,185	5.7
11	Alexei Zhitnik A. Zhitnik	822	712	55	234	289	-33	23	119	5	10	7	0	1,482	3.7	0	1	0.0	624	369	89	315	25:14
12	Adam Mair A. Mair	701	498	35	70	105	-10	1	1	1	0	5	0	482	7.3	971	2,007	48.4	656	125	67	108	9:17
13	Danny Gare D. Gare	686	503	267	233	500	+187	66	58	1	1	35		1,780	15.0
14	Dave Andreychuk D. Andreychuk	592	837	368	436	804	+22	161	180	0	0	38	4	2,342	15.7	93	187	49.7	36	25	31	36	12:00
15	Paul Gaustad P. Gaustad	585	479	71	110	181	+14	15	17	1	4	10	1	736	9.6	3,518	6,317	55.7	910	277	112	132	14:58
16	Andrew Peters A. Peters	557	200	4	3	7	-12	0	0	0	0	0	0	72	5.6	2	6	33.3	113	11	6	26	3:41
17	Gord Donnelly G. Donnelly	557	134	5	11	16	-1	0	0	0	1	1	0	65	7.7
18	Patrick Kaleta P. Kaleta	542	348	27	27	54	-18	0	0	3	1	5	1	324	8.3	26	64	40.6	866	218	55	55	9:54
19	Ric Seiling R. Seiling	524	664	176	200	376	+116	26	23	9	9	23	0	1,125	15.6
20	Kevin Maguire K. Maguire	518	167	18	25	43	+5	0	0	0	0	3	0	122	14.8
21	Eric Boulton E. Boulton	511	172	5	12	17	-3	0	0	0	0	1	0	94	5.3	2	9	22.2	137	24	11	38	5:52
22	Doug Bodger D. Bodger	506	479	54	233	287	+15	33	144	1	7	4	0	1,032	5.2
23	Gilbert Perreault G. Perreault	500	1,191	512	814	1,326	+41	134	298	8	4	81	0	3,077	16.6
24	Bob Boughner B. Boughner	494	177	2	11	13	+20	0	0	0	1	0	0	74	2.7
25	Christian Ruuttu C. Ruuttu	483	438	101	230	331	+16	22	68	8	6	10	0	925	10.9