Wayne Gretzky had the most games with 4+ points, with 217 games.

Interpreted as:

Most 4+ point regular-season games by a player in NHL history

	NAME	GP	P	G	A	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Wayne Gretzky W. Gretzky	217	1,004	343	661	+524	104	71	188	32	37	32	1	1,054	32.5
2	Mario Lemieux M. Lemieux	124	570	217	353	+252	87	80	158	22	10	22	1	652	33.3	106	229	46.3	3	2	10	5	23:17
3	Phil Esposito P. Esposito	70	302	130	172	+186	91	37	52	8	3	22	0	442	29.4
4	Marcel Dionne M. Dionne	63	270	112	158	+137	41	38	57	2	2	15	0	345	32.5
5	Mike Bossy M. Bossy	60	258	121	137	+154	8	38	39	0	0	17	0	294	41.2
6	Jaromir Jagr J. Jagr	56	237	90	147	+135	40	21	49	3	1	18	2	282	31.9	1	2	50.0	5	7	15	32	21:27
7	Steve Yzerman S. Yzerman	55	238	93	145	+128	59	16	51	15	4	14	1	281	33.1	35	55	63.6	1	1	2	2	20:22
8	Peter Stastny P. Stastny	54	235	99	136	+127	42	23	49	0	2	12	0	209	47.4
9	Bryan Trottier B. Trottier	49	214	70	144	+144	26	20	35	4	4	7	0	173	40.5
10	Jari Kurri J. Kurri	47	209	87	122	+152	10	17	27	7	14	8	0	200	43.5
11	Paul Coffey P. Coffey	45	198	56	142	+86	52	10	66	10	5	6	1	232	24.1
12	Dale Hawerchuk D. Hawerchuk	45	198	66	132	+81	28	21	57	1	1	7	0	201	32.8
13	Ron Francis R. Francis	44	190	65	125	+103	12	24	46	4	2	10	0	142	45.8	27	42	64.3	1	2	1	2	20:30
14	Sidney Crosby S. Crosby	43	180	58	122	+91	22	13	51	0	1	7	0	157	36.9	524	951	55.1	35	21	31	27	19:22
15	Brett Hull B. Hull	43	175	99	76	+86	14	38	23	6	1	11	0	249	39.8	0	0		1	0	6	6	17:00
16	Mark Messier M. Messier	42	174	72	102	+89	58	19	38	6	6	10	1	178	40.4
17	Gilbert Perreault G. Perreault	42	187	70	117	+90	20	16	38	2	0	10	0	169	41.4
18	Bobby Orr B. Orr	42	184	53	131	+147	47	17	35	3	7	8	0	246	21.5
19	Connor McDavid C. McDavid	41	177	61	116	+96	18	19	43	1	0	9	0	177	34.5	228	464	49.1	31	23	41	34	20:09
20	Adam Oates A. Oates	41	170	48	122	+84	22	16	41	1	3	9	0	118	40.7	66	109	60.6	0	4	3	7	20:24
21	Jean Beliveau J. Beliveau	40	169	78	91	+47	43	30	34	0	0	15	0	127	33.1
22	Guy Lafleur G. Lafleur	39	170	64	106	+102	16	21	31	0	1	7	0	192	33.3
23	Stan Mikita S. Mikita	39	165	69	96	+97	42	19	30	2	2	10	0	204	33.8
24	Teemu Selanne T. Selanne	38	161	74	87	+80	16	25	32	1	0	8	1	178	41.6	30	48	62.5	1	4	11	27	19:04
25	Gordie Howe G. Howe	38	159	72	87	+42	45	14	25	3	1	6	0	81	34.6