Between the 2000-01 and 2012-13 seasons, the Detroit Red Wings had the most wins by a team, with 572 wins.

Interpreted as:

most NHL regular-season wins 2000-01 to 2012-13

	TEAM	W	GP	L	T	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Red Wings	572	950	248	40	90	1,274	.671	38	41	2,963	2,351	612	20.8	84.1	32.68	9.5	27.11	.909
2	Devils	523	950	312	43	72	1,161	.611	56	36	2,517	2,250	267	17.1	84.0	29.79	8.9	26.25	.910
3	Canucks	521	950	307	41	81	1,164	.613	39	46	2,800	2,422	378	18.6	83.7	29.44	10.0	28.42	.910
4	Sharks	519	950	296	41	94	1,173	.617	44	40	2,721	2,365	356	19.3	83.3	30.32	9.4	27.87	.911
5	Senators	503	950	324	36	87	1,129	.594	28	41	2,876	2,492	384	18.9	83.9	30.66	9.9	28.50	.908
6	Stars	498	950	325	49	78	1,123	.591	53	36	2,610	2,438	172	17.5	83.0	28.06	9.8	27.22	.906
7	Flyers	481	950	329	49	91	1,102	.580	24	43	2,775	2,562	213	18.2	83.2	30.30	9.6	28.67	.906
8	Sabres	478	950	354	33	85	1,074	.565	50	41	2,708	2,549	159	17.3	84.3	29.55	9.6	29.64	.909
9	Bruins	476	950	328	40	106	1,098	.578	46	46	2,658	2,508	150	17.0	83.3	30.84	9.1	29.68	.911
10	Avalanche	472	950	356	44	78	1,066	.561	48	27	2,701	2,603	98	18.5	82.0	29.37	9.7	28.91	.905
11	Penguins	464	950	375	31	80	1,039	.547	54	30	2,778	2,826	-48	18.6	82.1	28.97	10.1	30.17	.901
12	Predators	463	950	360	46	81	1,053	.554	42	37	2,505	2,485	20	16.2	83.5	27.96	9.4	29.56	.912
13	Capitals	460	950	359	39	92	1,051	.553	33	42	2,737	2,740	-3	19.4	81.1	29.20	9.9	30.42	.905
14	Rangers	458	950	378	26	88	1,030	.542	54	40	2,572	2,552	20	16.6	82.7	30.09	9.0	29.21	.908
15	Ducks	453	950	362	38	97	1,041	.548	40	47	2,493	2,503	-10	18.6	83.1	28.72	9.1	29.54	.911
16	Blues	451	950	355	42	102	1,046	.551	39	47	2,534	2,509	25	17.1	83.7	28.54	9.3	26.84	.902
17	Canadiens	450	950	368	35	97	1,032	.543	38	43	2,582	2,580	2	18.7	83.2	28.55	9.5	30.73	.912
18	Maple Leafs	448	950	366	38	98	1,032	.543	29	45	2,734	2,788	-54	17.8	80.7	29.25	9.8	29.11	.899
19	Flames	444	950	366	47	93	1,028	.541	26	43	2,501	2,551	-50	16.5	82.4	28.35	9.3	28.39	.905
20	Blackhawks	440	950	370	45	95	1,020	.537	45	47	2,623	2,659	-36	15.7	82.7	29.77	9.3	28.06	.900
21	Kings	433	950	377	46	94	1,006	.529	48	41	2,527	2,582	-55	17.4	81.8	28.82	9.2	27.77	.902
22	Wild	431	950	381	55	83	1,000	.526	46	44	2,335	2,421	-86	16.3	84.7	26.43	9.3	29.52	.914
23	Hurricanes	430	950	380	50	90	1,000	.526	24	32	2,581	2,745	-164	16.3	82.0	30.30	9.0	29.49	.902
24	Coyotes	427	950	382	55	86	995	.524	46	42	2,469	2,656	-187	15.8	81.5	28.46	9.1	30.49	.908
25	Lightning	411	950	405	41	93	956	.503	35	36	2,593	2,863	-270	17.2	81.6	28.71	9.5	29.32	.897