Since 2006-07, the Boston Bruins have the most wins by an Eastern Conference team, with 793 wins.

NHL most conference semi-finals regular-season wins by eastern conference team since 2006-07

	TEAM	W	GP	L	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Bruins	793	1,378	423	162	1,748	.634	72	80	4,092	3,482	610	20.2	82.9	31.73	9.4	29.97	.916
2	Penguins	781	1,377	447	149	1,711	.621	86	60	4,285	3,818	467	20.2	82.6	31.97	9.7	30.36	.909
3	Capitals	762	1,374	448	164	1,688	.614	69	75	4,221	3,839	382	21.2	81.3	30.19	10.2	30.23	.908
4	Rangers	750	1,376	487	139	1,639	.596	83	71	3,949	3,599	350	19.1	82.9	30.60	9.4	30.14	.913
5	Lightning	734	1,374	502	138	1,606	.584	69	62	4,253	4,016	237	21.0	80.9	29.94	10.3	30.08	.903
6	Hurricanes	688	1,374	523	163	1,539	.560	45	68	3,924	3,862	62	18.3	82.5	32.05	8.9	29.06	.903
7	Maple Leafs	673	1,376	532	171	1,517	.551	64	75	4,154	4,188	-34	19.7	79.2	31.16	9.7	31.29	.903
8	Devils	670	1,378	550	158	1,498	.544	74	86	3,638	3,784	-146	18.6	82.7	29.30	9.0	28.89	.905
9	Panthers	663	1,376	533	180	1,506	.547	76	97	3,942	3,984	-42	18.8	80.5	31.86	9.0	31.37	.908
10	Canadiens	652	1,377	560	165	1,469	.533	79	73	3,791	4,001	-210	18.7	81.2	29.91	9.2	31.36	.907
11	Flyers	648	1,376	544	184	1,480	.538	56	92	3,929	4,083	-154	18.7	81.3	30.71	9.3	30.38	.902
12	Islanders	637	1,376	558	181	1,455	.529	79	81	3,789	4,055	-266	17.7	79.8	30.10	9.1	31.40	.906
13	Senators	635	1,377	586	156	1,426	.518	64	76	3,890	4,144	-254	18.2	80.7	30.74	9.2	31.57	.905
14	Sabres	605	1,376	607	164	1,374	.499	81	74	3,756	4,131	-375	18.5	80.2	29.95	9.1	31.94	.906
15	Blue Jackets	395	836	356	85	875	.523	39	25	2,385	2,568	-183	18.0	79.5	30.53	9.3	32.04	.904
16	Red Wings	354	837	369	114	822	.491	41	39	2,244	2,632	-388	19.1	78.6	29.00	9.2	31.24	.899
17	Jets	242	540	235	63	547	.506	38	31	1,491	1,681	-190	17.2	79.1	29.09	9.5	32.03	.903