Since 2006-07, the Boston Bruins have the most wins by an Eastern Conference team, with 793 wins.

NHL most conference semifinals regular-season wins by eastern conference team since 2006-07

	TEAM	W	GP	L	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Bruins	793	1,379	424	162	1,748	.634	72	80	4,093	3,487	606	20.2	82.9	31.73	9.4	29.96	.916
2	Penguins	782	1,378	447	149	1,713	.622	86	60	4,294	3,820	474	20.2	82.6	31.97	9.7	30.35	.909
3	Capitals	763	1,375	448	164	1,690	.615	69	75	4,223	3,840	383	21.2	81.3	30.19	10.2	30.23	.908
4	Rangers	750	1,376	487	139	1,639	.596	83	71	3,949	3,599	350	19.1	82.9	30.60	9.4	30.14	.913
5	Lightning	735	1,375	502	138	1,608	.585	69	62	4,261	4,019	242	21.0	80.9	29.94	10.4	30.08	.903
6	Hurricanes	688	1,374	523	163	1,539	.560	45	68	3,924	3,862	62	18.3	82.5	32.05	8.9	29.06	.903
7	Maple Leafs	674	1,377	532	171	1,519	.552	64	75	4,157	4,190	-33	19.7	79.2	31.16	9.7	31.29	.903
8	Devils	671	1,379	550	158	1,500	.544	74	86	3,641	3,785	-144	18.6	82.7	29.29	9.0	28.88	.905
9	Panthers	663	1,377	534	180	1,506	.547	76	97	3,942	3,988	-46	18.7	80.5	31.85	9.0	31.36	.908
10	Canadiens	652	1,378	561	165	1,469	.533	79	73	3,793	4,010	-217	18.6	81.2	29.90	9.2	31.36	.907
11	Flyers	649	1,377	544	184	1,482	.538	56	92	3,933	4,084	-151	18.7	81.3	30.72	9.3	30.38	.902
12	Islanders	638	1,377	558	181	1,457	.529	79	81	3,794	4,059	-265	17.6	79.8	30.09	9.2	31.40	.906
13	Senators	635	1,377	586	156	1,426	.518	64	76	3,890	4,144	-254	18.2	80.7	30.74	9.2	31.57	.905
14	Sabres	605	1,376	607	164	1,374	.499	81	74	3,756	4,131	-375	18.5	80.2	29.95	9.1	31.94	.906
15	Blue Jackets	395	837	356	86	876	.523	39	25	2,386	2,570	-184	18.0	79.5	30.53	9.3	32.05	.904
16	Red Wings	354	838	370	114	822	.490	41	39	2,245	2,636	-391	19.1	78.6	28.99	9.2	31.25	.899
17	Jets	242	540	235	63	547	.506	38	31	1,491	1,681	-190	17.2	79.1	29.09	9.5	32.03	.903