Between the 2006-07 and 2020-21 seasons, the Pittsburgh Penguins had the most wins by a team, with 682 wins.

Interpreted as:

NHL most regular-season wins from 2006-07 to 2020-21

	TEAM	W	GP	L	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Penguins	682	1,157	361	114	1,478	.639	82	48	3,610	3,126	484	20.5	82.7	31.51	9.9	30.05	.910
2	Capitals	660	1,157	363	134	1,454	.628	61	65	3,561	3,171	390	21.5	81.5	30.29	10.2	30.23	.909
3	Bruins	648	1,158	369	141	1,437	.620	66	74	3,363	2,908	455	20.1	83.0	31.69	9.2	29.93	.916
4	Sharks	644	1,158	389	125	1,413	.610	75	60	3,339	3,048	291	20.7	82.5	31.78	9.1	28.50	.908
5	Blues	620	1,159	405	134	1,374	.593	70	61	3,208	3,019	189	18.6	83.2	29.51	9.4	28.28	.908
6	Predators	620	1,157	403	134	1,374	.594	68	67	3,233	3,060	173	17.3	81.6	30.06	9.3	29.91	.912
7	Lightning	614	1,158	427	117	1,345	.581	62	55	3,481	3,337	144	20.0	81.1	29.82	10.1	29.99	.904
8	Blackhawks	610	1,158	410	138	1,358	.586	73	64	3,410	3,202	208	17.8	80.7	31.53	9.3	30.06	.908
9	Ducks	609	1,159	407	143	1,361	.587	68	71	3,151	3,100	51	19.0	82.0	29.37	9.3	30.18	.911
10	Rangers	608	1,158	429	121	1,337	.577	72	64	3,235	3,025	210	18.0	82.9	30.49	9.2	30.13	.913
11	Wild	598	1,157	431	128	1,324	.572	66	67	3,120	3,044	76	18.8	82.6	28.68	9.4	29.75	.912
12	Stars	584	1,157	436	137	1,305	.564	61	61	3,211	3,189	22	18.3	80.9	29.73	9.3	29.47	.906
13	Canucks	583	1,157	447	127	1,293	.559	68	72	3,156	3,144	12	18.7	82.6	29.67	9.2	30.61	.911
14	Canadiens	582	1,159	437	140	1,304	.563	67	63	3,195	3,164	31	19.1	82.3	30.46	9.0	30.72	.911
15	Flames	577	1,158	461	120	1,274	.550	50	58	3,255	3,265	-10	18.0	81.3	29.50	9.5	29.45	.904
16	Red Wings	572	1,159	428	159	1,303	.562	67	73	3,192	3,218	-26	18.9	81.0	31.17	8.8	29.20	.905
17	Flyers	566	1,157	438	153	1,285	.555	49	86	3,343	3,353	-10	19.7	81.5	30.67	9.4	30.28	.904
18	Avalanche	564	1,158	482	112	1,240	.535	70	36	3,229	3,356	-127	18.3	80.5	29.92	9.3	30.90	.906
19	Jets	563	1,159	471	125	1,251	.540	68	54	3,317	3,419	-102	18.3	79.6	29.87	9.6	31.47	.906
20	Devils	554	1,157	463	140	1,248	.539	69	80	2,882	3,084	-202	17.8	82.6	28.64	8.7	28.87	.908
21	Kings	551	1,158	473	134	1,236	.534	63	70	3,003	3,054	-51	18.2	81.7	30.30	8.6	28.53	.908
22	Hurricanes	548	1,156	462	146	1,242	.537	42	59	3,179	3,293	-114	17.6	81.8	31.62	8.7	29.64	.904
23	Maple Leafs	541	1,158	469	148	1,230	.531	56	70	3,370	3,531	-161	18.7	78.9	30.82	9.4	31.45	.903
24	Islanders	540	1,156	470	146	1,226	.530	77	67	3,149	3,385	-236	17.5	80.3	30.13	9.0	31.17	.906
25	Blue Jackets	539	1,158	482	137	1,215	.525	63	69	3,062	3,275	-213	16.3	81.1	29.86	8.9	30.23	.906