The Arizona Coyotes had the highest moneyline by a team in a game with a goal differential above 1 in 2021-22, at +431 versus the Wild on April 26, 2022.
| TEAM | DIFF | DATE | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | G | GA | PPG | PPO | OPP PPG | OPP PPO | S | SA | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Coyotes | 2 | 4/26/2022 |  ARI | +431 | @ |  MIN | -601 | W 5-3 | +1.5 | +3.5 (Y) | 6.5 | +1.5 (O) | 5 | 3 | 1 | 4 | 0 | 6 | 26 | 38 |
| 2 |  | Blue Jackets | 3 | 2/24/2022 |  CBJ | +356 | @ |  FLA | -478 | W 6-3 | +1.5 | +4.5 (Y) | 7 | +2 (O) | 6 | 3 | 0 | 2 | 0 | 4 | 28 | 42 |
| 3 |  | Sabres | 3 | 4/12/2022 |  BUF | +336 | @ |  TOR | -440 | W 5-2 | +1.5 | +4.5 (Y) | 7 | 0 (P) | 5 | 2 | 2 | 4 | 0 | 5 | 28 | 26 |
| 4 | | Sabres | 4 | 3/2/2022 | BUF | +316 | @ | TOR | -410 | W 5-1 | +1.5 | +5.5 (Y) | 6.5 | -0.5 (U) | 5 | 1 | 1 | 2 | 0 | 1 | 31 | 30 |
| 5 |  | Canadiens | 3 | 2/21/2022 |  MTL | +314 | vs | TOR | -406 | W 5-2 | +1.5 | +4.5 (Y) | 6.5 | +0.5 (O) | 5 | 2 | 0 | 2 | 0 | 2 | 24 | 37 |
| 6 |  | Red Wings | 3 | 4/14/2022 |  DET | +295 | @ |  CAR | -382 | W 3-0 | +1.5 | +4.5 (Y) | 6.5 | -3.5 (U) | 3 | 0 | 0 | 1 | 0 | 3 | 22 | 46 |
| 7 | | Canadiens | 2 | 1/18/2022 | MTL | +281 | @ |  DAL | -363 | W 5-3 | +1.5 | +3.5 (Y) | 5.5 | +2.5 (O) | 5 | 3 | 1 | 3 | 1 | 8 | 22 | 51 |
| 8 | | Sabres | 3 | 1/13/2022 | BUF | +276 | @ |  NSH | -361 | W 4-1 | +1.5 | +4.5 (Y) | 6 | -1 (U) | 4 | 1 | 1 | 4 | 1 | 4 | 21 | 30 |
| 9 | | Sabres | 3 | 3/13/2022 | BUF | +241 | vs | TOR | -301 | W 5-2 | +1.5 | +4.5 (Y) | 6.5 | +0.5 (O) | 5 | 2 | 0 | 4 | 0 | 3 | 38 | 36 |
| 10 | | Blue Jackets | 6 | 1/13/2022 | CBJ | +233 | @ | CAR | -288 | W 6-0 | +1.5 | +7.5 (Y) | 6 | 0 (P) | 6 | 0 | 0 | 1 | 0 | 1 | 35 | 31 |
| 11 |  | Senators | 3 | 1/13/2022 |  OTT | +232 | @ |  CGY | -287 | W 4-1 | +1.5 | +4.5 (Y) | 6 | -1 (U) | 4 | 1 | 0 | 3 | 0 | 1 | 34 | 28 |
| 12 | | Red Wings | 2 | 4/6/2022 | DET | +229 | @ |  WPG | -289 | W 3-1 | +1.5 | +3.5 (Y) | 6.5 | -2.5 (U) | 3 | 1 | 0 | 4 | 0 | 3 | 35 | 33 |
| 13 |  | Canucks | 2 | 3/23/2022 |  VAN | +229 | @ |  COL | -284 | W 3-1 | +1.5 | +3.5 (Y) | 6.5 | -2.5 (U) | 3 | 1 | 0 | 1 | 1 | 5 | 27 | 33 |
| 14 |  | Devils | 5 | 2/24/2022 |  NJD | +229 | @ |  PIT | -284 | W 6-1 | +1.5 | +6.5 (Y) | 6.5 | +0.5 (O) | 6 | 1 | 2 | 5 | 1 | 4 | 36 | 38 |
| 15 |  | Penguins | 4 | 10/12/2021 | PIT | +226 | @ |  TBL | -282 | W 6-2 | +1.5 | +5.5 (Y) | 5.5 | +2.5 (O) | 6 | 2 | 0 | 1 | 0 | 1 | 35 | 28 |
| 16 | | Sabres | 2 | 4/5/2022 | BUF | +224 | vs | CAR | -280 | W 4-2 | +1.5 | +3.5 (Y) | 6 | 0 (P) | 4 | 2 | 1 | 3 | 0 | 2 | 22 | 34 |
| 17 |  | Kings | 4 | 11/8/2021 |  LAK | +221 | @ | TOR | -277 | W 5-1 | +1.5 | +5.5 (Y) | 5.5 | +0.5 (O) | 5 | 1 | 0 | 3 | 1 | 2 | 29 | 34 |
| 18 | | Blue Jackets | 3 | 4/28/2022 | CBJ | +218 | vs | TBL | -267 | W 5-2 | +1.5 | +4.5 (Y) | 6.5 | +0.5 (O) | 5 | 2 | 1 | 4 | 2 | 7 | 35 | 27 |
| 19 | | Senators | 3 | 3/8/2022 | OTT | +218 | @ |  STL | -270 | W 4-1 | +1.5 | +4.5 (Y) | 6 | -1 (U) | 4 | 1 | 2 | 2 | 0 | 1 | 28 | 23 |
| 20 |  | Kraken | 2 | 1/23/2022 |  SEA | +218 | vs | FLA | -268 | W 5-3 | +1.5 | +3.5 (Y) | 6 | +2 (O) | 5 | 3 | 0 | 4 | 1 | 3 | 29 | 31 |
| 21 |  | Ducks | 4 | 1/21/2022 |  ANA | +217 | vs | TBL | -272 | W 5-1 | +1.5 | +5.5 (Y) | 5.5 | +0.5 (O) | 5 | 1 | 1 | 5 | 0 | 7 | 35 | 33 |
| 22 | | Senators | 6 | 12/14/2021 | OTT | +217 | @ | FLA | -270 | W 8-2 | +1.5 | +7.5 (Y) | 6.5 | +3.5 (O) | 8 | 2 | 2 | 4 | 0 | 6 | 38 | 35 |
| 23 | | Coyotes | 2 | 2/25/2022 | ARI | +215 | vs |  VGK | -267 | W 3-1 | +1.5 | +3.5 (Y) | 5.5 | -1.5 (U) | 3 | 1 | 0 | 3 | 0 | 2 | 32 | 44 |
| 24 |  | Predators | 2 | 2/22/2022 | NSH | +214 | @ | FLA | -265 | W 6-4 | +1.5 | +3.5 (Y) | 7 | +3 (O) | 6 | 4 | 1 | 3 | 1 | 3 | 33 | 48 |
| 25 | | Sabres | 2 | 12/14/2021 | BUF | +212 | @ | WPG | -266 | W 4-2 | +1.5 | +3.5 (Y) | 5.5 | +0.5 (O) | 4 | 2 | 1 | 2 | 0 | 3 | 27 | 36 |
Oilers 
Bruins 
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