Between the 2020 and 2029 seasons, A'ja Wilson dropped the most points in a game, with 53 points against the Dream on August 22, 2023.

Interpreted as:

most points by a player in a regular-season game in the 2020s

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	A'ja Wilson A. Wilson	53	8/22/2023	LVA	@	ATL	33	7	0	0	4	16	23	69.6	1	1	100.0	20	21	95.2	82.2	0	7	2	3	+24
2	Breanna Stewart B. Stewart	45	5/21/2023	NYL	vs	IND	30	12	3	1	1	15	21	71.4	6	9	66.7	9	9	100.0	90.1	0	12	1	3	+27
3	Paige Bueckers P. Bueckers	44	8/20/2025	DAL	@	LAS	36	4	3	1	0	17	21	81.0	4	4	100.0	6	6	100.0	93.1	0	4	3	3	+12
4	Breanna Stewart B. Stewart	43	7/5/2023	NYL	vs	PHX	38	12	6	1	2	13	20	65.0	3	4	75.0	14	16	87.5	79.5	1	11	2	2	+11
5	Rhyne Howard R. Howard	43	7/2/2023	ATL	vs	LAS	32	2	4	2	2	14	20	70.0	6	12	50.0	9	9	100.0	89.7	0	2	3	5	+26
6	A'ja Wilson A. Wilson	42	8/27/2024	LVA	@	DAL	37	6	2	1	3	16	22	72.7	0	2	0.0	10	13	76.9	75.8	2	4	1	2	0
7	Breanna Stewart B. Stewart	42	8/13/2023	NYL	@	IND	36	6	6	3	3	15	23	65.2	5	10	50.0	7	8	87.5	79.2	2	4	1	3	+11
8	Diana Taurasi D. Taurasi	42	8/3/2023	PHX	vs	ATL	30	4	2	0	0	12	21	57.1	6	13	46.2	12	12	100.0	79.9	1	3	3	3	+31
9	A'ja Wilson A. Wilson	41	9/1/2024	LVA	@	PHX	34	17	2	2	1	16	23	69.6	2	6	33.3	7	9	77.8	76.0	4	13	0	3	+20
10	Jewell Loyd J. Loyd	41	6/29/2023	SEA	vs	MIN	40	9	2	1	0	15	35	42.9	4	9	44.4	7	8	87.5	53.2	4	5	6	1	+1
11	Arike Ogunbowale A. Ogunbowale	41	6/17/2023	DAL	vs	SEA	38	3	3	2	1	13	24	54.2	7	14	50.0	8	8	100.0	74.5	0	3	3	5	-2
12	DeWanna Bonner D. Bonner	41	6/8/2023	CON	vs	LVA	32	7	1	1	0	16	23	69.6	5	7	71.4	4	5	80.0	81.3	2	5	0	3	+29
13	Arike Ogunbowale A. Ogunbowale	40	5/25/2024	DAL	@	PHX	38	7	4	4	0	11	24	45.8	7	12	58.3	11	12	91.7	68.3	0	7	3	1	+18
14	Breanna Stewart B. Stewart	40	9/5/2023	NYL	@	DAL	34	10	2	1	1	14	25	56.0	3	7	42.9	9	13	69.2	65.1	3	7	0	2	+5
15	Satou Sabally S. Sabally	40	9/1/2023	DAL	@	IND	29	7	4	0	0	13	19	68.4	7	10	70.0	7	7	100.0	90.6	1	6	2	5	+7
16	A'ja Wilson A. Wilson	40	8/11/2023	LVA	vs	WAS	31	12	1	2	1	17	25	68.0	0	1	0.0	6	7	85.7	71.2	1	11	1	3	+16
17	Kelsey Plum K. Plum	40	7/9/2023	LVA	@	MIN	31	2	4	0	0	14	18	77.8	6	9	66.7	6	6	100.0	96.9	0	2	2	2	+26
18	Jewell Loyd J. Loyd	39	7/11/2023	SEA	@	WAS	35	4	3	0	0	11	22	50.0	9	16	56.3	8	9	88.9	75.1	1	3	1	3	+8
19	Jewell Loyd J. Loyd	39	6/17/2023	SEA	@	DAL	38	5	5	0	0	12	22	54.5	7	13	53.8	8	10	80.0	73.9	3	2	4	4	+4
20	Arike Ogunbowale A. Ogunbowale	39	9/6/2020	DAL	@	WAS	41	3	4	1	0	12	24	50.0	4	6	66.7	11	12	91.7	66.6	1	2	0	0	+12
21	Kelsey Mitchell K. Mitchell	38	8/17/2025	IND	@	CON	40	1	6	2	0	11	22	50.0	5	8	62.5	11	12	91.7	69.6	1	0	3	1	+14
22	Breanna Stewart B. Stewart	38	9/15/2024	NYL	vs	MIN	36	18	1	2	0	12	27	44.4	3	6	50.0	11	13	84.6	58.1	6	12	1	4	-10
23	Kahleah Copper K. Copper	38	5/18/2024	PHX	vs	ATL	33	6	1	0	0	11	20	55.0	3	5	60.0	13	16	81.3	70.3	1	5	2	4	0
24	Breanna Stewart B. Stewart	38	8/26/2023	NYL	@	MIN	27	11	2	0	2	12	17	70.6	6	8	75.0	8	8	100.0	92.6	1	10	0	1	+36
25	Jewell Loyd J. Loyd	38	8/14/2022	SEA	@	LVA	35	1	0	0	0	13	23	56.5	8	14	57.1	4	4	100.0	76.7	0	1	5	2	-9