A'ja Wilson and Liz Cambage are tied for the most points per game in a game, with 53.0 per game.

Interpreted as:

most points per game by a player in a single regular-season game

	NAME	PPG	DATE	TM		OPP	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	A'ja Wilson A. Wilson	53.0	8/22/2023	LVA	@	ATL	33	53	7	0	0	4	16	23	69.6	1	1	100.0	20	21	95.2	82.2	0	7	2	3	+24
2	Liz Cambage L. Cambage	53.0	7/17/2018	DAL	vs	NYL	37	53	10	2	1	5	17	22	77.3	4	5	80.0	15	16	93.8	91.3	1	9	0	1	+17
3	Riquna Williams R. Williams	51.0	9/8/2013	TUL	@	SAN	35	51	1	3	0	0	17	28	60.7	8	14	57.1	9	9	100.0	79.8	0	1	0	2	+34
4	Maya Moore M. Moore	48.0	7/22/2014	MIN	vs	ATL	46	48	10	4	2	1	16	30	53.3	7	9	77.8	9	11	81.8	68.9	2	8	5	4	+10
5	Lauren Jackson L. Jackson	47.0	7/24/2007	SEA	@	WAS	42	47	14	1	0	0	18	28	64.3	2	4	50.0	9	11	81.8	71.6	4	10	1	5	+3
6	Diana Taurasi D. Taurasi	47.0	8/10/2006	PHX	@	HOU	44	47	6	9	1	1	17	33	51.5	8	16	50.0	5	7	71.4	65.1	1	5	2	6	+5
7	Katie Smith K. Smith	46.0	7/8/2001	MIN	@	LAS	45	46	3	4	0	0	11	23	47.8	6	10	60.0	18	19	94.7	73.3	0	3	1	4	-5
8	Breanna Stewart B. Stewart	45.0	5/21/2023	NYL	vs	IND	30	45	12	3	1	1	15	21	71.4	6	9	66.7	9	9	100.0	90.1	0	12	1	3	+27
9	Elena Delle Donne E. Delle Donne	45.0	6/24/2015	CHI	vs	ATL	44	45	11	0	2	6	12	20	60.0	2	4	50.0	19	19	100.0	79.3	1	10	5	5	+7
10	Paige Bueckers P. Bueckers	44.0	8/20/2025	DAL	@	LAS	36	44	4	3	1	0	17	21	81.0	4	4	100.0	6	6	100.0	93.1	0	4	3	3	+12
11	Diana Taurasi D. Taurasi	44.0	7/14/2010	PHX	vs	SEA	49	44	5	5	4	2	16	33	48.5	4	11	36.4	8	9	88.9	59.5	0	5	5	5	-2
12	Betty Lennox B. Lennox	44.0	6/27/2008	ATL	@	CON	39	44	9	7	3	0	17	32	53.1	5	12	41.7	5	6	83.3	63.5	3	6	2	3	-7
13	Deanna Nolan D. Nolan	44.0	6/20/2008	DET	vs	MIN	45	44	5	3	1	0	15	22	68.2	4	8	50.0	10	10	100.0	83.3	0	5	3	6	+3
14	Cynthia Cooper C. Cooper	44.0	7/25/1997	HOU	@	SAC	34	44	6	3	1	0	14	21	66.7	7	9	77.8	9	9	100.0	88.1	1	5	1	4	+12
15	Breanna Stewart B. Stewart	43.0	7/5/2023	NYL	vs	PHX	38	43	12	6	1	2	13	20	65.0	3	4	75.0	14	16	87.5	79.5	1	11	2	2	+11
16	Rhyne Howard R. Howard	43.0	7/2/2023	ATL	vs	LAS	32	43	2	4	2	2	14	20	70.0	6	12	50.0	9	9	100.0	89.7	0	2	3	5	+26
17	Liz Cambage L. Cambage	43.0	8/17/2018	DAL	vs	LVA	34	43	13	3	0	0	14	20	70.0	2	2	100.0	13	16	81.3	79.5	7	6	3	5	-1
18	Kristi Toliver K. Toliver	43.0	7/3/2015	LAS	vs	TUL	38	43	1	9	1	0	15	24	62.5	7	12	58.3	6	6	100.0	80.7	0	1	4	5	+3
19	A'ja Wilson A. Wilson	42.0	8/27/2024	LVA	@	DAL	37	42	6	2	1	3	16	22	72.7	0	2	0.0	10	13	76.9	75.8	2	4	1	2	0
20	Breanna Stewart B. Stewart	42.0	8/13/2023	NYL	@	IND	36	42	6	6	3	3	15	23	65.2	5	10	50.0	7	8	87.5	79.2	2	4	1	3	+11
21	Diana Taurasi D. Taurasi	42.0	8/3/2023	PHX	vs	ATL	30	42	4	2	0	0	12	21	57.1	6	13	46.2	12	12	100.0	79.9	1	3	3	3	+31
22	Cynthia Cooper C. Cooper	42.0	8/16/1999	HOU	vs	UTA	35	42	1	3	1	0	11	18	61.1	3	5	60.0	17	18	94.4	81.0	0	1	5	0	+11
23	A'ja Wilson A. Wilson	41.0	9/1/2024	LVA	@	PHX	34	41	17	2	2	1	16	23	69.6	2	6	33.3	7	9	77.8	76.0	4	13	0	3	+20
24	Jewell Loyd J. Loyd	41.0	6/29/2023	SEA	vs	MIN	40	41	9	2	1	0	15	35	42.9	4	9	44.4	7	8	87.5	53.2	4	5	6	1	+1
25	Arike Ogunbowale A. Ogunbowale	41.0	6/17/2023	DAL	vs	SEA	38	41	3	3	2	1	13	24	54.2	7	14	50.0	8	8	100.0	74.5	0	3	3	5	-2