4 players are tied for the most interceptions in a game, with 4 interceptions. The first three are Quinyon Mitchell on October 8, 2022, Damon Nickson on October 28, 2006 and Junior Rosegreen on October 2, 2004.

most defensive interceptions by a player in a single game cfb

	NAME	INT	DATE	TM		OPP	TKL	AST	COMB	SCK	SCKY	INT YDS	INT TD	FF	FR	FR TD
1	Quinyon Mitchell Q. Mitchell	4	10/8/2022	TOL	@	NIU	1	2	3	0.0	0	45	2	0	0
2	Damon Nickson D. Nickson	4	10/28/2006	MTSU	@	UL	5	1	6			30	1		0	0
3	Junior Rosegreen J. Rosegreen	4	10/2/2004	AUB	@	TENN						0	0		0	0
4	Lamont Thompson L. Thompson	4	11/3/2001	WSU	vs	UCLA						39	0		0	0
5	Josh Moten J. Moten	3	11/8/2025	USM	@	ARST	4	2	6	0.0	0	22	0	0	0	0
6	Phillip Dunnam P. Dunnam	3	11/7/2025	UCF	vs	HOU	3	1	4	0.0	0	81	1	0	0	0
7	Cam Chadwick C. Chadwick	3	11/1/2025	CONN	vs	UAB	5	2	7	1.0	6	9	0	0	0	0
8	Cobee Bryant C. Bryant	3	10/19/2024	KU	vs	HOU	2	1	3	0.0	0	21	0	0	0	0
9	Devin Grant D. Grant	3	10/7/2023	BUFF	vs	CMU	5	0	5	0.0	0	87	2	0	0
10	Carlton Johnson C. Johnson	3	9/16/2023	FRES	@	ASU	2	1	3	0.0	0	0	0	0	0	0
11	Clayton Isbell C. Isbell	3	9/2/2023	CCAR	@	UCLA	5	4	9	0.0	0	29	0	0	0	0
12	Benjamin Morrison B. Morrison	3	11/19/2022	ND	vs	BC	1	0	1	0.0	0	0	0	0	0
13	Kamren Kinchens K. Kinchens	3	11/12/2022	MIA	@	GT	0	0	0	0.0	0	99	1	0	0
14	Marcus Fuqua M. Fuqua	3	10/22/2022	BUFF	vs	TOL	0	0	0	0.0	0	21	0	0	0	0
15	Clark Phillips III C. Phillips III	3	10/1/2022	UTAH	vs	ORST	1	2	3	0.0	0	57	1	0	0
16	Steven Jones S. Jones	3	11/6/2021	APP	@	ARST	0	0	0	0.0	0	83	2	0	0
17	Montre Miller M. Miller	3	9/11/2021	KENT	vs	VMI	0	0	0	0.0	0	3	0	0	0
18	Nick Andersen N. Andersen	3	10/24/2020	WAKE	vs	VT	9	2	11	0.0	0	0	0	0	0
19	Hudson Clark H. Clark	3	10/17/2020	ARK	vs	MISS	3	2	5	0.0	0	18	0	0	0
20	Bryce Thompson B. Thompson	3	11/2/2019	TENN	vs	UAB	3	0	3	0.0	0	28	0	0	0
21	Amik Robertson A. Robertson	3	10/19/2019	LT	vs	USM	2	1	3	0.0	0	19	0	0	0
22	Israel Mukuamu I. Mukuamu	3	10/12/2019	SC	@	UGA	8	3	11	0.0	0	53	1	0	0	0
23	Luq Barcoo L. Barcoo	3	10/5/2019	SDSU	@	CSU	5	1	6	0.0	0	5	0	0	0
24	Jaylinn Hawkins J. Hawkins	3	12/26/2018	CAL	@	TCU	6	0	6	0.0	0	29	0	0	0	0
25	Mark McLaurin M. McLaurin	3	12/30/2017	MSST	vs	LOU	0	0	0	0.0	0	42	0	0	0