Jordan Ayew has scored the most career goals by a Ghanaian in the Premier League, with 42 goals.

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Jordan Ayew J. Ayew	42	305	21,479	246	0.14	25	67	3	0	396	135	10	12,052	729	66
2	Tony Yeboah T. Yeboah	24	47	3,874	44	0.51	3	27	0
3	Antoine Semenyo A. Semenyo	23	86	6,023	68	0.27	9	32	1	0	212	78	7	3,314	370	21
4	Jeffrey Schlupp J. Schlupp	22	280	16,775	188	0.08	14	36	0	0	232	75	3	9,489	334	3
5	André Ayew A. Ayew	21	102	6,529	70	0.21	9	30	0	1	131	54	5	3,240	117	21
6	Michael Essien M. Essien	17	169	13,356	150	0.10	10	27	0
7	Mohammed Kudus M. Kudus	13	70	5,533	63	0.19	12	25	0	0	150	40	8	3,337	272	36
8	Asamoah Gyan A. Gyan	10	34	2,233	23	0.29	4	14	0
9	Thomas Partey T. Partey	9	130	9,643	109	0.07	5	14	0	0	132	29	4	8,291	104	1
10	Sulley Muntari S. Muntari	5	38	2,911	34	0.13	5	10	1
11	Kamal Deen Sulemana K. Deen Sulemana	3	44	2,373	27	0.07	2	5	0	0	54	15	2	1,162	113	5
12	Tariq Lamptey T. Lamptey	3	104	5,280	57	0.03	9	12	0	0	44	8	0	3,672	130	7
13	Christian Atsu C. Atsu	3	80	4,121	41	0.04	6	9	0	0	72	28	0	2,021	126	14
14	Kevin-Prince Boateng K. Boateng	3	36	2,448	27	0.08	2	5	1
15	Daniel Amartey D. Amartey	2	107	7,342	80	0.02	1	3	0	0	30	11	0	5,627	33	2
16	John Mensah J. Mensah	1	34	2,266	29	0.03	1	2	0
17	Alex Nyarko A. Nyarko	1	33	2,289	26	0.03	0	1	0