Since 2020-21, Salernitana have the lowest goal differential by a club against a club in Serie A, with a differential of -20 goals against Inter.
| CLUB | GD | OPP | M | W | D | L | G | GC | XG | XGA | SH | SOT | PASS-ATT | PASS | POSS% | FOUL | YC | RC | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Salernitana | -20 |  Inter | 6 | 0 | 1 | 5 | 1 | 21 | 3.46 | 18.40 | 53 | 14 | 2,024 | 1,627 | 36.4 | 66 | 8 | 0 |
| 2 |  Verona | -19 | Inter | 9 | 0 | 1 | 8 | 5 | 24 | 83 | 23 | 3,299 | 2,596 | 39.9 | 112 | 17 | 1 | ||
| 3 |  Empoli | -16 |  Atalanta | 8 | 1 | 0 | 7 | 5 | 21 | 5.61 | 20.57 | 74 | 22 | 2,993 | 2,297 | 41.7 | 80 | 15 | 0 |
| 4 |  Udinese | -16 |  Napoli | 10 | 0 | 3 | 7 | 10 | 26 | 95 | 32 | 3,463 | 2,815 | 36.5 | 130 | 15 | 1 | ||
| 5 |  Cagliari | -16 | Inter | 8 | 0 | 1 | 7 | 5 | 21 | 68 | 21 | 2,948 | 2,402 | 36.8 | 93 | 8 | 0 | ||
| 6 |  Sassuolo | -16 |  Napoli | 8 | 1 | 2 | 5 | 9 | 25 | 76 | 31 | 3,479 | 2,971 | 43.0 | 76 | 17 | 2 | ||
| 7 |  Lecce | -15 | Inter | 6 | 0 | 0 | 6 | 1 | 16 | 4.65 | 13.35 | 73 | 20 | 2,031 | 1,659 | 37.9 | 84 | 10 | 1 |
| 8 |  Spezia | -15 |  Lazio | 6 | 0 | 0 | 6 | 6 | 21 | 58 | 16 | 2,760 | 2,273 | 45.7 | 85 | 16 | 2 | ||
| 9 | Empoli | -14 |  Milan | 8 | 0 | 1 | 7 | 3 | 17 | 5.40 | 12.55 | 78 | 16 | 2,876 | 2,333 | 41.2 | 108 | 15 | 1 |
| 10 | Empoli | -14 | Inter | 8 | 1 | 0 | 7 | 4 | 18 | 4.40 | 15.22 | 69 | 22 | 2,786 | 2,260 | 36.2 | 103 | 10 | 2 |
| 11 | Udinese | -14 | Inter | 10 | 1 | 1 | 8 | 10 | 24 | 93 | 27 | 3,558 | 2,923 | 38.5 | 119 | 15 | 0 | ||
| 12 | Verona | -14 | Atalanta | 10 | 2 | 1 | 7 | 9 | 23 | 120 | 33 | 3,995 | 2,932 | 44.2 | 135 | 24 | 0 | ||
| 13 | Atalanta | -14 | Inter | 10 | 0 | 3 | 7 | 8 | 22 | 132 | 35 | 4,598 | 3,859 | 48.0 | 137 | 26 | 2 | ||
| 14 | Empoli | -13 |  Roma | 8 | 2 | 0 | 6 | 7 | 20 | 10.44 | 16.53 | 100 | 29 | 3,097 | 2,562 | 43.2 | 106 | 18 | 1 |
| 15 | Verona | -13 | Milan | 10 | 0 | 1 | 9 | 8 | 21 | 105 | 27 | 3,207 | 2,333 | 40.0 | 153 | 26 | 0 | ||
| 16 | Cagliari | -12 | Milan | 8 | 0 | 3 | 5 | 7 | 19 | 95 | 29 | 2,804 | 2,262 | 39.0 | 81 | 16 | 0 | ||
| 17 | Udinese | -12 |  Juventus | 9 | 1 | 1 | 7 | 5 | 17 | 107 | 28 | 3,375 | 2,820 | 40.5 | 101 | 16 | 0 | ||
| 18 |  Sampdoria | -12 | Napoli | 6 | 0 | 0 | 6 | 1 | 13 | 59 | 19 | 2,126 | 1,658 | 35.9 | 70 | 12 | 1 | ||
| 19 |  Genoa | -12 |  Fiorentina | 8 | 0 | 3 | 5 | 6 | 18 | 67 | 19 | 2,744 | 2,138 | 40.1 | 121 | 20 | 0 | ||
| 20 |  Torino | -12 | Inter | 9 | 0 | 1 | 8 | 6 | 18 | 96 | 39 | 3,300 | 2,636 | 39.3 | 110 | 9 | 2 | ||
| 21 | Spezia | -12 | Juventus | 6 | 0 | 0 | 6 | 3 | 15 | 74 | 20 | 2,697 | 2,280 | 48.1 | 71 | 10 | 0 | ||
| 22 |  Monza | -11 | Atalanta | 5 | 0 | 0 | 5 | 3 | 14 | 4.02 | 10.03 | 48 | 14 | 2,896 | 2,461 | 56.9 | 45 | 12 | 1 |
| 23 | Monza | -11 | Roma | 6 | 0 | 2 | 4 | 3 | 14 | 4.44 | 9.23 | 56 | 19 | 2,695 | 2,325 | 47.9 | 65 | 15 | 1 |
| 24 |  Venezia | -11 | Milan | 4 | 0 | 0 | 4 | 0 | 11 | 2.95 | 9.14 | 38 | 8 | 1,458 | 1,197 | 39.9 | 50 | 7 | 2 |
| 25 | Fiorentina | -11 | Napoli | 10 | 2 | 2 | 6 | 10 | 21 | 110 | 32 | 4,615 | 3,889 | 50.7 | 142 | 20 | 1 | ||
Bologna 
COM 
PAR 
