Lazio have the lowest goal differential by a club in Serie A, with a differential of -1,607 goals.

	CLUB	GD	M	W	D	L	G	GC	POSS%	YC	RC
1	Lazio	-1,607	913	0	0	913	508	2,115	51.7	926	172
2	Fiorentina	-1,498	895	0	0	895	497	1,995	54.3	943	139
3	Torino	-1,497	856	0	0	856	432	1,929	49.4	821	126
4	Bologna	-1,480	875	0	0	875	495	1,975	50.0	969	142
5	Roma	-1,467	874	0	0	874	506	1,973	54.5	808	148
6	Atalanta	-1,461	816	0	0	816	420	1,881	53.0	968	139
7	Sampdoria	-1,455	823	0	0	823	447	1,902	48.1	950	124
8	Genoa	-1,398	770	0	0	770	466	1,864	47.2	840	103
9	Napoli	-1,314	758	0	0	758	454	1,768	59.3	637	128
10	Udinese	-1,289	712	0	0	712	431	1,720	45.3	1,035	103
11	Inter	-1,089	697	0	0	697	435	1,524	57.6	648	93
12	Milan	-1,063	685	0	0	685	433	1,496	53.3	645	96
13	Cagliari	-1,019	599	0	0	599	313	1,332	44.9	1,056	119
14	Bari	-931	466	0	0	466	245	1,176		373	78
15	Juventus	-895	559	0	0	559	322	1,217	54.1	453	81
16	Palermo	-876	439	0	0	439	220	1,096	45.4	455	70
17	Verona	-829	478	0	0	478	256	1,085	44.5	671	83
18	Triestina	-710	353	0	0	353	224	934		0	34
19	Vicenza	-699	390	0	0	390	193	892		158	40
20	Brescia	-659	355	0	0	355	175	834	38.5	399	65
21	Lecce	-648	340	0	0	340	194	842	43.8	725	69
22	Parma	-605	356	0	0	356	219	824	45.1	827	69
23	Livorno	-588	283	0	0	283	175	763		269	38
24	Empoli	-531	287	0	0	287	149	680	48.3	562	47
25	Padova	-526	248	0	0	248	158	684		75	27