Shay Given has made the most career appearances by an Irishman in the Premier League, with 451 appearances.

	NAME	M	MIN	START	G	G/M	A	G+A	PK
1	Shay Given S. Given	451	40,216	451	0	0.00	2	2	0
2	John O'Shea J. O'Shea	445	33,068	370	13	0.03	13	26	0
3	Richard Dunne R. Dunne	431	36,794	419	11	0.03	5	16	0
4	Damien Duff D. Duff	392	28,643	327	54	0.14	55	109	0
5	Stephen Carr S. Carr	377	32,742	371	8	0.02	18	26	0
6	Séamus Coleman S. Coleman	372	28,913	327	22	0.06	24	46	0
7	Roy Keane R. Keane	366	30,839	349	39	0.11	33	72	0
8	Rory Delap R. Delap	359	28,431	327	23	0.06	21	44	0
9	Robbie Keane R. Keane	349	24,461	273	126	0.36	37	163	17
10	Shane Long S. Long	344	17,809	186	56	0.16	21	77	1
11	Kenny Cunningham K. Cunningham	335	29,618	334	0	0.00	16	16	0
12	Denis Irwin D. Irwin	328	27,889	316	18	0.05	25	43	7
13	Kevin Kilbane K. Kilbane	325	24,581	275	15	0.05	18	33	0
14	Gary Kelly G. Kelly	325	28,397	316	2	0.01	31	33	0
15	Jeff Kenna J. Kenna	290	25,176	282	8	0.03	20	28	0
16	Steve Staunton S. Staunton	288	23,568	271	13	0.05	28	41	1
17	Lee Carsley L. Carsley	282	22,744	253	16	0.06	12	28	1
18	Andy O'Brien A. O'Brien	280	23,661	265	8	0.03	2	10	0
19	Glenn Whelan G. Whelan	276	20,839	235	4	0.01	12	16	0
20	James McCarthy J. McCarthy	272	20,915	237	13	0.05	12	25	0
21	Niall Quinn N. Quinn	250	17,958	200	59	0.24	37	96	0
22	Stephen Ireland S. Ireland	246	15,232	169	19	0.08	28	47	0
23	Ian Harte I. Harte	237	19,766	217	28	0.12	36	64	10
24	Steve Finnan S. Finnan	236	20,162	224	1	0.00	14	15	0
25	Jon Walters J. Walters	233	16,740	189	43	0.18	19	62	10