Ciro Immobile has tallied the most career goals by a striker in Serie A, with 148 goals.

	NAME	G	RTG	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Ciro Immobile C. Immobile	148		215	17,916	215	0.69	38	186	42	0	716	332	33	7,962	1,362	173
2	Lautaro Martínez L. Martínez	93		190	15,555	190	0.49	23	116	9	0	669	247	19	6,637	1,147	90
3	Duván Zapata D. Zapata	84		185	14,828	185	0.45	30	114	4	0	522	216	12	7,063	1,239	99
4	Dušan Vlahović D. Vlahović	77		148	12,269	148	0.52	15	92	21	5	487	185	13	4,735	797	105
5	Romelu Lukaku R. Lukaku	76		142	12,061	142	0.54	26	102	14	0	337	148	13	4,366	776	96
6	Fabio Quagliarella F. Quagliarella	74		150	12,324	150	0.49	22	96	25	0	499	185	10	4,968	674	136
7	Edin Džeko E. Džeko	73		166	14,210	166	0.44	32	105	0	0	610	235	20	6,373	1,043	69
8	Andrea Belotti A. Belotti	70		193	16,345	193	0.36	22	92	19	0	564	204	23	6,960	954	138
9	Victor Osimhen V. Osimhen	60		89	7,488	89	0.67	11	71	5	0	353	141	11	2,498	625	100
10	Francesco Caputo F. Caputo	60		161	13,589	161	0.37	19	79	9	0	312	144	8	4,528	820	144
11	Dries Mertens D. Mertens	55		100	7,966	100	0.55	25	80	6	2	323	130	13	3,976	537	42
12	Giovanni Simeone G. Simeone	50		161	12,843	161	0.31	15	65	0	0	377	133	8	4,801	660	124
13	Andrea Pinamonti A. Pinamonti	47		178	14,842	178	0.26	8	55	8	0	417	135	9	5,485	729	72
14	Cristiano Ronaldo C. Ronaldo	45		57	5,041	57	0.79	9	54	9	0	302	122	7	3,090	380	51
15	Mauro Icardi M. Icardi	45		65	5,689	65	0.69	6	51	11	0	181	88	5	1,528	347	54
16	Olivier Giroud O. Giroud	37	6.53	74	5,746	74	0.50	15	52	9	0	202	87	4	2,104	367	34
17	Moise Kean M. Kean	37		83	6,484	83	0.45	4	41	2	0	224	92	5	2,038	332	99
18	Andrea Petagna A. Petagna	37		142	11,270	142	0.26	16	53	12	0	299	108	6	4,890	619	46
19	Arkadiusz Milik A. Milik	36		72	5,709	72	0.50	3	39	0	4	214	103	13	2,252	301	39
20	João Pedro J. Pedro	34		96	8,410	96	0.35	9	43	10	1	218	87	6	3,351	383	46
21	Antonio Sanabria A. Sanabria	33		124	9,623	124	0.27	8	41	2	0	242	92	10	3,756	403	46
22	Paulo Dybala P. Dybala	33		84	6,547	84	0.39	18	51	6	0	256	99	9	5,095	329	20
23	Leonardo Pavoletti L. Pavoletti	33		95	7,938	95	0.35	3	36	0	0	227	85	6	3,367	417	63
24	Mattia Destro M. Destro	32		80	5,894	80	0.40	5	37	0	0	155	74	5	1,918	269	63
25	Zlatan Ibrahimovic Z. Ibrahimovic	31		42	3,423	42	0.74	8	39	6	2	170	68	7	1,969	309	63