Gianluigi Buffon has the most career minutes in Serie A, with 58,536 minutes.

most minutes by a player ever

	NAME	MIN	M	START	G	G/M	A	G+A	PK
1	Gianluigi Buffon G. Buffon	58,536	657	655	0	0.00	0	0	0
2	Paolo Maldini P. Maldini	56,495	647	640	29	0.04			0
3	Gianluca Pagliuca G. Pagliuca	53,150	592	592	0	0.00			0
4	Javier Zanetti J. Zanetti	53,018	615	589	12	0.02	6	18	0
5	Dino Zoff D. Zoff	51,274	570	570	0	0.00			0
6	Samir Handanovič S. Handanovič	50,577	566	565	0	0.00	0	0	0
7	Pietro Vierchowod P. Vierchowod	49,531	562	557	38	0.07			0
8	Silvio Piola S. Piola	48,070	537	537	274	0.51			24
9	Enrico Albertosi E. Albertosi	47,400	532	531	0	0.00			0
10	Francesco Totti F. Totti	47,054	618	540	250	0.40	46	296	71
11	Gianni Rivera G. Rivera	46,999	526	525	129	0.25			27
12	Andrea Consigli A. Consigli	45,538	510	510	0	0.00	0	0	0
13	Giuseppe Bergomi G. Bergomi	45,012	519	510	23	0.04			0
14	Tarcisio Burgnich T. Burgnich	44,218	493	493	6	0.01			0
15	Giovanni Galli G. Galli	44,060	496	489	0	0.00			0
16	Roberto Mancini R. Mancini	43,935	541	497	156	0.29			22
17	Giancarlo De Sisti G. De Sisti	42,910	478	478	50	0.10			4
18	Giacinto Facchetti G. Facchetti	42,717	475	475	59	0.12			0
19	Pietro Ferraris P. Ferraris	42,165	469	469	125	0.27			1
20	Sergio Cervato S. Cervato	41,940	466	466	45	0.10			24
21	Franco Baresi F. Baresi	41,716	470	470	12	0.03			7
22	Ciro Ferrara C. Ferrara	41,455	499	469	27	0.05			0
23	Angelo Peruzzi A. Peruzzi	41,414	478	475	0	0.00			0
24	Sébastien Frey S. Frey	39,925	446	443	0	0.00	0	0	0
25	Gian Piero Boniperti G. Piero Boniperti	39,690	443	443	179	0.40			2