I don't have anything for this season, but Napoli had the most points by a club in Serie A in 2024-25, with 82 points.

most points lost after being ahead this season

	CLUB	POINTS	L	SEASON	M	W	D	G	GC	xG	xGA	SH	SOT	PASS-ATT	PASS	POSS%	FOUL	YC	RC
1	Napoli	82	4	2024-25	38	24	10	59	27	53.57	30.62	504	157	18,637	16,170	54.6	415	47	0
2	Inter	81	5	2024-25	38	24	9	79	35	68.94	36.24	574	192	21,187	18,682	59.8	417	56	1
3	Atalanta	74	8	2024-25	38	22	8	78	37	68.16	41.04	545	194	19,486	16,627	55.3	435	67	1
4	Juventus	70	4	2024-25	38	18	16	58	35	51.49	36.02	515	188	19,953	17,592	57.6	480	67	3
5	Roma	69	9	2024-25	38	20	9	56	35	54.93	42.05	522	177	18,904	16,326	53.9	405	66	1
6	Lazio	65	9	2024-25	38	18	11	61	49	57.63	39.18	536	200	18,042	15,672	55.1	424	93	7
7	Fiorentina	65	11	2024-25	38	19	8	60	41	49.87	43.50	446	175	16,287	13,633	50.5	440	82	3
8	Milan	63	11	2024-25	38	18	9	61	43	65.09	42.34	564	196	17,915	15,732	54.1	415	70	6
9	Bologna	62	8	2024-25	38	16	14	57	47	50.54	37.28	512	174	17,807	14,925	58.6	537	61	4
10	Como	49	15	2024-25	38	13	10	49	52	45.80	44.17	520	179	17,895	15,219	54.8	503	87	7
11	Torino	44	14	2024-25	38	10	14	39	45	35.64	51.08	386	130	15,644	12,866	47.5	483	80	3
12	Udinese	44	18	2024-25	38	12	8	41	56	40.15	53.21	434	143	14,968	12,353	47.2	540	88	5
13	Genoa	43	15	2024-25	38	10	13	37	49	38.00	47.90	385	123	14,374	11,402	45.6	497	71	1
14	Verona	37	21	2024-25	38	10	7	34	66	34.73	54.69	374	98	12,333	9,351	38.5	579	98	9
15	Cagliari	36	20	2024-25	38	9	9	40	56	43.19	57.66	424	122	14,270	11,323	44.7	500	68	3
16	Parma	36	16	2024-25	38	7	15	44	58	45.68	59.17	425	148	14,755	12,003	44.2	405	78	6
17	Lecce	34	20	2024-25	38	8	10	27	58	34.77	58.02	454	126	13,765	10,830	43.5	465	61	7
18	Empoli	31	19	2024-25	38	6	13	33	59	33.36	51.59	369	111	12,552	9,431	41.3	568	68	5
19	Venezia	29	19	2024-25	38	5	14	32	56	38.61	59.42	387	128	13,846	10,928	44.8	503	75	2
20	Monza	18	26	2024-25	38	3	9	28	69	31.62	56.59	334	103	16,227	13,602	48.6	512	90	3