Since 1999-00, Juventus have the most wins by a club in Serie A, with 585 wins.

	CLUB	W	M	D	L	G	GC	POSS%	YC	RC
1	Juventus	585	936	220	131	1,679	783	55.4	1,847	96
2	Inter	553	974	228	193	1,775	987	57.2	1,936	102
3	Milan	516	974	251	207	1,641	997	53.9	2,023	137
4	Roma	514	974	242	218	1,707	1,075	54.8	2,177	137
5	Lazio	458	974	235	281	1,539	1,156	52.5	2,286	165
6	Napoli	389	724	170	165	1,272	773	59.7	1,460	71
7	Fiorentina	363	906	250	293	1,299	1,106	54.0	2,045	102
8	Udinese	334	974	257	383	1,240	1,343	44.4	2,160	132
9	Atalanta	324	830	229	277	1,216	1,042	52.9	1,936	111
10	Bologna	252	822	243	327	954	1,119	51.6	1,981	114
11	Sampdoria	235	718	189	294	882	993	48.7	1,783	98
12	Parma	223	708	204	281	893	1,024	43.9	1,656	99
13	Torino	208	716	238	270	840	966	49.5	1,711	96
14	Cagliari	198	762	217	347	849	1,156	45.1	1,866	122
15	Genoa	193	652	186	273	754	923	46.8	1,624	102
16	Chievo	186	634	185	263	659	837	44.2	1,593	96
17	Palermo	150	456	127	179	587	677	45.6	1,145	73
18	Sassuolo	136	424	115	173	576	680	50.1	1,027	59
19	Verona	133	488	129	226	559	774	44.3	1,195	89
20	Empoli	125	486	137	224	495	720	47.7	1,046	54
21	Lecce	110	484	144	230	520	787	43.2	1,160	88
22	Catania	86	304	90	128	335	425		763	55
23	Siena	83	338	107	148	356	472		822	50
24	Reggina	83	326	107	136	324	467		764	46
25	Brescia	61	250	81	108	281	374	40.2	608	44