Andrea Pirlo has the most career wins by a midfielder in Serie A, with 276 wins.

	NAME	W	M	MIN	START	G	G/M	A	G+A	PK
1	Andrea Pirlo A. Pirlo	276	493	37,349	414	58	0.12	31	89	14
2	Daniele De Rossi D. De Rossi	249	459	37,196	428	43	0.09	21	64	4
3	Gianni Rivera G. Rivera	245	526	46,999	525	129	0.25			27
4	Mario Corso M. Corso	228	436	38,890	436	78	0.18			4
5	Marek Hamšík M. Hamšík	222	409	31,502	375	100	0.24	64	164	7
6	Piotr Zieliński P. Zieliński	221	400	24,033	261	45	0.11	52	97	3
7	Juan Cuadrado J. Cuadrado	219	405	27,826	302	44	0.11	63	107	2
8	Massimo Ambrosini M. Ambrosini	217	392	26,325	296	30	0.08	5	35	0
9	Dejan Stanković D. Stanković	215	368	27,061	306	51	0.14	7	58	0
10	Clarence Seedorf C. Seedorf	215	396	29,239	334	58	0.15	7	65	0
11	Lorenzo Insigne L. Insigne	210	336	23,961	278	96	0.29	75	171	27
12	Franco Causio F. Causio	210	460	38,472	431	66	0.14			12
13	Pavel Nedvěd P. Nedvěd	206	352	28,599	330	73	0.21			0
14	Giuseppe Furino G. Furino	202	388	33,268	377	9	0.02			0
15	Gennaro Gattuso G. Gattuso	201	368	27,367	321	9	0.02	2	11	0
16	Nils Erik Liedholm N. Erik Liedholm	198	359	32,310	359	81	0.23			25
17	Antonio Candreva A. Candreva	194	502	36,702	424	85	0.17	79	164	22
18	David Pizarro D. Pizarro	193	381	29,902	334	28	0.07	10	38	17
19	Carlo Reguzzoni C. Reguzzoni	191	400	35,865	400	156	0.39			19
20	Antonio Conte A. Conte	187	372	26,610	302	30	0.08			0
21	Carlo Annovazzi C. Annovazzi	187	391	35,145	391	65	0.17			11
22	Giacomo Mari G. Mari	187	426	38,340	426	24	0.06			7
23	Claudio Marchisio C. Marchisio	186	295	23,204	265	33	0.11	21	54	1
24	Teobaldo Depetrini T. Depetrini	185	400	36,000	400	9	0.02			0
25	Esteban Cambiasso E. Cambiasso	184	315	25,710	290	41	0.13	9	50	0