who has scored the most goals against the big six all time

Alan Shearer has tallied the most career goals in the Premier League against Big Six opponents, with 56 goals.

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Alan Shearer A. Shearer	56	129	11,314	126	0.43	19	75	7
2	Mohamed Salah M. Salah	50	81	6,712	76	0.62	22	72	11
3	Jamie Vardy J. Vardy	45	108	8,408	95	0.42	10	55	8	0	188	92	8	2,258	328	88
4	Wayne Rooney W. Rooney	45	135	10,635	117	0.33	14	59	6
5	Sergio Agüero S. Agüero	44	75	5,630	69	0.59	8	52	6
6	Jimmy Floyd Hasselbaink J. Floyd Hasselbaink	41	81	5,793	66	0.51	11	52	3
7	Harry Kane H. Kane	39	81	7,007	78	0.48	9	48	11
8	Thierry Henry T. Henry	34	61	5,181	57	0.56	13	47	3
9	Dion Dublin D. Dublin	34	92	7,047	79	0.37	13	47	5
10	Robbie Fowler R. Fowler	33	90	6,386	70	0.37	10	43	3
11	Andy Cole A. Cole	32	109	8,470	95	0.29	13	45	0
12	Darren Bent D. Bent	31	76	5,287	56	0.41	5	36	4
13	Les Ferdinand L. Ferdinand	31	93	6,907	78	0.33	13	44	0
14	Sadio Mané S. Mané	29	79	6,196	71	0.37	9	38	0	0	153	76	4	3,686	286	65
15	Robin van Persie R. van Persie	28	75	5,554	61	0.37	11	39	3
16	Jermain Defoe J. Defoe	28	136	8,646	91	0.21	6	34	5
17	Marcus Rashford M. Rashford	27	82	5,719	64	0.33	9	36	4	0	130	65	6	2,436	274	39
18	Son Heung-min S. Heung-min	27	88	6,420	76	0.31	9	36	1	0	173	79	5	3,170	289	59
19	Mark Viduka M. Viduka	27	74	5,413	59	0.36	3	30	2
20	Frank Lampard F. Lampard	26	158	12,798	144	0.16	21	47	10
21	Roberto Firmino R. Firmino	25	70	5,255	62	0.36	9	34	1	0	149	69	4	3,313	329	24
22	Teddy Sheringham T. Sheringham	25	106	7,846	88	0.24	12	37	5
23	Christian Benteke C. Benteke	24	83	5,792	64	0.29	9	33	1
24	Kevin De Bruyne K. De Bruyne	23	77	5,896	67	0.30	19	42	2
25	Gylfi Þór Sigurðsson G. Þór Sigurðsson	23	98	7,452	82	0.23	11	34	5