Pepe Reina has the most career clean sheets per match in the Premier League, with 0.46 per match.

Interpreted as:

most clean sheets per game with a minimum of 15000 min by a player all-time

	NAME	CS/M	MIN	CS	M	START	GC	GC/M	SV	SV-PK	ERR-SH	ERR-G	OG	TKL	FOUL	YC	RC	W-D-L
1	Pepe Reina P. Reina	0.46	26,713	136	297	297	252	0.85		2			1			10	2	W150 D76 L71
2	Petr Čech P. Čech	0.46	39,495	202	443	442	362	0.82		1			2			6	1	W280 D87 L76
3	Tony Adams T. Adams	0.45	22,434	115	255	252	182	0.71		0			2			36	4	W132 D67 L56
4	Nemanja Vidić N. Vidić	0.45	18,083	95	211	205	145	0.69		0			1			47	6	W149 D35 L27
5	Ederson	0.44	24,515	122	277	276	216	0.78	467	3	16	6	0	14	10	24	1	W206 D34 L37
6	John Terry J. Terry	0.43	41,969	214	492	473	370	0.75		0			4			75	6	W311 D107 L74
7	Edwin van der Sar E. van der Sar	0.42	27,921	133	313	312	293	0.94		0			0			11	0	W166 D71 L76
8	Peter Schmeichel P. Schmeichel	0.41	27,595	128	310	310	279	0.90		0			0			5	0	W175 D80 L55
9	Alisson	0.41	21,073	97	235	235	210	0.89	570	2	10	11	1	10	4	4	1	W156 D49 L30
10	David Seaman D. Seaman	0.41	30,753	140	344	344	277	0.81		0			1			1	1	W171 D100 L73
11	Gary Pallister G. Pallister	0.40	22,771	104	261	261	230	0.88		0			2			27	1	W144 D68 L49
12	Sami Hyypiä S. Hyypiä	0.39	27,448	125	318	310	259	0.81		0			2			16	1	W172 D73 L73
13	Ashley Cole A. Cole	0.38	33,152	148	385	372	314	0.82		0			1			63	3	W240 D88 L57
14	Jamie Carragher J. Carragher	0.38	43,267	195	508	484	423	0.83		0			7			70	2	W264 D124 L120
15	Virgil van Dijk V. van Dijk	0.38	27,735	119	312	311	305	0.98	0	0	7	5	0	313	158	27	2	W195 D65 L52
16	William Gallas W. Gallas	0.38	27,453	122	321	305	260	0.81		0			2			39	1	W184 D80 L57
17	Rio Ferdinand R. Ferdinand	0.38	43,890	189	504	492	454	0.90		0			5			36	1	W291 D110 L103
18	Denis Irwin D. Irwin	0.38	27,889	123	328	316	288	0.88		0			1			25	1	W185 D86 L57
19	Lee Dixon L. Dixon	0.37	25,714	114	305	288	244	0.80		0			1			30	1	W152 D88 L65
20	Joe Hart J. Hart	0.37	30,489	127	340	340	373	1.10		4			0			7	0	W169 D74 L97
21	Gary Neville G. Neville	0.37	33,573	148	400	380	328	0.82		0			2			53	2	W256 D87 L57
22	Nigel Martyn N. Martyn	0.37	33,296	137	372	371	404	1.09		0			1			7	0	W154 D98 L120
23	Frank Lampard F. Lampard	0.36	48,871	219	609	546	491	0.81		0			1			59	3	W349 D133 L127
24	Mark Bosnich M. Bosnich	0.36	18,200	74	206	206	198	0.96		0			1			8	1	W93 D52 L61
25	Vincent Kompany V. Kompany	0.36	22,267	95	265	253	211	0.80		0			3			60	3	W167 D50 L48