Gareth Barry has made the most career appearances in the Premier League, with 653 appearances.

	NAME	M	MIN	START	G	G/M	A	G+A	PK
1	Gareth Barry G. Barry	653	54,434	618	53	0.08	64	117	18
2	James Milner J. Milner	645	40,285	434	56	0.09	88	144	18
3	Ryan Giggs R. Giggs	632	46,437	522	109	0.17	163	272	2
4	Frank Lampard F. Lampard	609	48,871	546	177	0.29	102	279	43
5	David James D. James	572	51,298	571	0	0.00	2	2	0
6	Gary Speed G. Speed	535	46,319	521	80	0.15	44	124	10
7	Emile Heskey E. Heskey	516	38,108	445	110	0.21	53	163	0
8	Mark Schwarzer M. Schwarzer	514	46,181	514	0	0.00	1	1	0
9	Jamie Carragher J. Carragher	508	43,267	484	3	0.01	15	18	0
10	Phil Neville P. Neville	505	39,857	446	9	0.02	25	34	0
11	Steven Gerrard S. Gerrard	504	41,129	466	121	0.24	89	210	31
12	Rio Ferdinand R. Ferdinand	504	43,890	492	11	0.02	8	19	0
13	Sol Campbell S. Campbell	503	43,321	488	20	0.04	15	35	0
14	Paul Scholes P. Scholes	499	36,129	404	107	0.21	54	161	1
15	Jermain Defoe J. Defoe	496	32,631	347	162	0.33	33	195	14
16	John Terry J. Terry	492	41,969	473	41	0.08	12	53	0
17	Wayne Rooney W. Rooney	491	38,027	421	208	0.42	100	308	23
18	Ashley Young A. Young	485	36,894	411	50	0.10	74	124	5
19	Michael Carrick M. Carrick	481	38,052	421	24	0.05	40	64	0
20	Sylvain Distin S. Distin	469	40,618	451	7	0.01	6	13	0
21	Peter Crouch P. Crouch	468	28,485	310	107	0.23	58	165	1
22	Aaron Hughes A. Hughes	455	38,823	434	5	0.01	14	19	0
23	Shay Given S. Given	451	40,216	451	0	0.00	2	2	0
24	Brad Friedel B. Friedel	450	40,428	450	1	0.00	0	1	0
25	John O'Shea J. O'Shea	445	33,068	370	13	0.03	13	26	0