Between the 2009-10 and 2019-20 seasons, Antonio Di Natale scored the most goals in Serie A, with 136 goals.

most goals by a player 2009-10 to 2019-20

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Antonio Di Natale A. Di Natale	136	228	17,651	202	0.60	27	163	25
2	Ciro Immobile C. Immobile	135	224	17,458	196	0.60	35	170	33
3	Gonzalo Higuaín G. Higuaín	125	224	17,108	193	0.56	29	154	12
4	Fabio Quagliarella F. Quagliarella	123	321	23,065	267	0.38	30	153	28
5	Mauro Icardi M. Icardi	121	219	17,197	193	0.55	27	148	19
6	Dries Mertens D. Mertens	93	236	14,204	148	0.39	47	140	10
7	Edinson Cavani E. Cavani	91	138	11,406	128	0.66	12	103	17
8	Rodrigo Palacio R. Palacio	88	321	23,297	260	0.27	46	134	4
9	Josip Iličić J. Iličić	87	291	19,423	226	0.30	47	134	11
10	Andrea Belotti A. Belotti	85	213	15,995	174	0.40	22	107	19	0	561	215	24	6,936	759	156
11	Paulo Dybala P. Dybala	84	222	15,490	175	0.38	40	124	17
12	Marek Hamšík M. Hamšík	82	339	26,085	310	0.24	64	146	5
13	Duván Zapata D. Zapata	81	196	12,892	145	0.41	24	105	3
14	Alessandro Matri A. Matri	80	280	15,339	167	0.29	14	94	6
15	Edin Džeko E. Džeko	78	172	13,457	146	0.45	31	109	3	0	666	269	24	6,185	961	89
16	Giampaolo Pazzini G. Pazzini	76	244	14,593	145	0.31	8	84	21
17	Alberto Gilardino A. Gilardino	75	233	17,848	199	0.32	13	88	7
18	Francesco Totti F. Totti	72	200	13,434	156	0.36	46	118	27
19	Mattia Destro M. Destro	70	231	13,848	155	0.30	12	82	2
20	Domenico Berardi D. Berardi	69	208	16,471	194	0.33	45	114	22
21	Luis Muriel L. Muriel	67	218	12,939	140	0.31	24	91	12
22	Cyril Théréau C. Théréau	66	259	18,362	214	0.25	17	83	8
23	Luca Toni L. Toni	66	167	12,182	136	0.40	16	82	11
24	Lorenzo Insigne L. Insigne	66	270	18,778	217	0.24	59	125	11
25	Marco Borriello M. Borriello	65	209	13,437	151	0.31	16	81	6