Lionel Messi has the most career goals in LaLiga against Real Madrid, with 18 goals.

most goals by a player scored against real madrid all-time

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Lionel Messi L. Messi	18	29	2,532	28	0.62	3	21	4
2	Silvestre Igoa S. Igoa	17	20	1,800	20	0.85			0
3	Telmo Zarra T. Zarra	17	17	1,530	17	1.00			0
4	Guillermo Gorostiza G. Gorostiza	17	25	2,250	25	0.68			1
5	Juan Arza J. Arza	15	24	2,160	24	0.63			1
6	Marcelino Guillermo García M. Guillermo García	15	17	1,530	17	0.88			0
7	César Rodríguez C. Rodríguez	14	28	2,520	28	0.50			0
8	Edmundo Suárez E. Suárez	13	18	1,620	18	0.72			0
9	Quini	11	26	2,089	23	0.42			2
10	José Luis Panizo J. Luis Panizo	11	26	2,340	26	0.42			0
11	Luis Suárez L. Suárez	10	14	1,162	13	0.71	2	12	1	0	40	20	2	586	57	8
12	Darko Kovačević D. Kovačević	10	15	1,233	14	0.67			1
13	Lyuboslav Mladenov Penev L. Mladenov Penev	10	17	1,352	15	0.59			2
14	Daniel Ruiz-Bazán D. Ruiz-Bazán	10	20	1,537	17	0.50			3
15	Manuel Badenes M. Badenes	10	13	1,170	13	0.77			0
16	José Juncosa J. Juncosa	10	17	1,530	17	0.59			0
17	Antoine Griezmann A. Griezmann	9	31	2,298	25	0.29	1	10	0
18	Xabi Prieto X. Prieto	9	21	1,685	19	0.43	2	11	4
19	Mehmed Kodro M. Kodro	9	15	1,217	14	0.60			2
20	Adrián Escudero A. Escudero	9	20	1,800	20	0.45			1
21	Manuel Hermida M. Hermida	9	11	990	11	0.82			0
22	Esteban Echevarría E. Echevarría	9	6	540	6	1.50			0
23	Joselu	8	10	753	8	0.80	0	8	1	0	32	15	1	359	39	3
24	Samuel Eto'o S. Eto'o	8	16	1,343	16	0.50			0
25	Germán Dévora G. Dévora	8	22	1,898	21	0.36			4