Before 2022-23, Robbie Fowler had the most goals by a Liverpool player in the Premier League against Big Six opponents, with 29 goals.

most goals by a player vs the big 6 all-time for liverpool until 2022

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Robbie Fowler R. Fowler	29	57	4,274	46	0.51	6	35	3
2	Mohamed Salah M. Salah	28	49	4,206	48	0.57	10	38	6	0	164	72	2	2,293	385	21
3	Roberto Firmino R. Firmino	22	62	4,863	58	0.35	8	30	1	0	143	65	4	3,051	304	23
4	Steven Gerrard S. Gerrard	22	129	10,736	123	0.17	23	45	8
5	Sadio Mané S. Mané	20	57	4,580	53	0.35	5	25	0	0	111	55	4	2,691	286	44
6	Michael Owen M. Owen	20	50	3,703	42	0.40	5	25	2
7	Fernando Torres F. Torres	16	26	2,015	23	0.62	2	18	0
8	Dirk Kuyt D. Kuyt	13	57	4,705	54	0.23	8	21	2
9	Ian Rush I. Rush	13	33	2,773	30	0.39	2	15	0
10	Philippe Coutinho P. Coutinho	12	40	3,091	37	0.30	4	16	0
11	Luis Suárez L. Suárez	11	32	2,717	30	0.34	5	16	0
12	Patrik Berger P. Berger	11	34	2,176	23	0.32	5	16	0
13	Steve McManaman S. McManaman	11	56	4,893	54	0.20	11	22	0
14	Diogo Jota D. Jota	9	15	842	9	0.60	2	11	0	0	28	16	1	439	66	2
15	Martin Škrtel M. Škrtel	9	65	5,643	63	0.14	1	10	0
16	Daniel Sturridge D. Sturridge	8	32	1,744	18	0.25	4	12	0
17	Jordan Henderson J. Henderson	8	87	6,752	77	0.09	9	17	1
18	Jamie Redknapp J. Redknapp	8	52	4,249	47	0.15	6	14	2
19	John Barnes J. Barnes	7	36	3,032	36	0.19	5	12	1
20	Georginio Wijnaldum G. Wijnaldum	5	48	3,717	42	0.10	2	7	0	0	54	24	0	2,508	76	2
21	James Milner J. Milner	5	54	3,389	37	0.09	2	7	3	0	30	10	0	3,003	36	2
22	Raheem Sterling R. Sterling	5	25	2,014	23	0.20	3	8	0
23	Harry Kewell H. Kewell	5	25	2,025	22	0.20	0	5	0
24	John Arne Riise J. Arne Riise	5	60	4,811	54	0.08	2	7	0
25	Sami Hyypiä S. Hyypiä	5	76	6,420	73	0.07	0	5	0