The Houston Astros have a record of 46-45 against the Guardians all-time.

	TEAM	DATE	REC	TM		OPP	RESULT	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Astros	6/30/1997	0-1	HOU	vs	CLE	L 4-6	.000	31	4	8	0	0	0	4	4	1	7	2	3	37	8	0	1	0	0	0	.258	.361	.258	.619
2	Astros	7/1/1997	0-1	HOU	vs	CLE	L 6-8	.000	35	6	10	2	0	1	4	4	0	4	0	1	40	15	3	1	0	0	0	.286	.359	.429	.788
3	Astros	7/2/1997	1-0	HOU	vs	CLE	W 6-2	1.000	31	6	10	1	3	0	6	5	0	6	1	2	37	17	4	0	1	1	1	.323	.405	.548	.954
4	Astros	6/26/1998	0-1	HOU	@	CLE	L 2-4	.000	31	2	5	1	0	0	1	1	0	8	0	0	32	6	1	0	0	0	2	.161	.188	.194	.381
5	Astros	6/27/1998	1-0	HOU	@	CLE	W 9-5	1.000	47	9	15	2	0	3	9	5	0	6	2	1	52	26	5	0	0	0	0	.319	.385	.553	.938
6	Astros	6/28/1998	1-0	HOU	@	CLE	W 12-3	1.000	38	12	16	3	0	2	12	5	0	8	0	0	46	25	5	1	2	0	1	.421	.467	.658	1.125
7	Astros	7/18/1999	1-0	HOU	vs	CLE	W 2-0	1.000	28	2	4	1	0	0	2	5	0	6	3	0	33	5	1	0	0	2	0	.143	.273	.179	.451
8	Astros	7/19/1999	1-0	HOU	vs	CLE	W 3-2	1.000	34	3	4	1	0	0	2	7	1	10	0	0	45	5	1	3	0	2	0	.118	.286	.147	.433
9	Astros	7/20/1999	0-1	HOU	vs	CLE	L 1-7	.000	33	1	6	1	0	1	1	0	1	6	0	0	34	10	2	0	0	0	1	.182	.206	.303	.509
10	Astros	7/16/2000	1-0	HOU	@	CLE	W 5-1	1.000	34	5	9	0	0	2	5	6	1	8	0	0	41	15	2	0	0	0	2	.265	.390	.441	.831
11	Astros	7/17/2000	0-1	HOU	@	CLE	L 6-8	.000	32	6	8	1	0	2	5	7	0	5	1	1	39	15	3	0	0	0	2	.250	.385	.469	.853
12	Astros	7/18/2000	0-1	HOU	@	CLE	L 2-8	.000	35	2	11	2	0	1	2	3	0	7	0	0	38	16	3	0	0	0	4	.314	.368	.457	.826
13	Astros	7/15/2001	1-0	HOU	vs	CLE	W 5-3	1.000	30	5	9	1	0	1	5	5	2	9	0	1	38	13	2	0	1	1	0	.300	.421	.433	.854
14	Astros	7/16/2001	1-0	HOU	vs	CLE	W 10-8	1.000	37	10	15	5	0	1	10	8	0	5	1	0	47	23	6	1	1	2	1	.405	.500	.622	1.122
15	Astros	7/17/2001	0-1	HOU	vs	CLE	L 4-10	.000	35	4	9	3	0	0	4	1	0	7	0	0	37	12	3	1	0	0	0	.257	.278	.343	.621
16	Astros	6/22/2012	0-1	HOU	vs	CLE	L 0-2	.000	30	0	4	1	0	0	0	4	0	12	1	0	34	5	1	0	0	0	0	.133	.235	.167	.402
17	Astros	6/23/2012	1-0	HOU	vs	CLE	W 8-1	1.000	33	8	10	6	0	3	8	1	0	5	0	1	34	25	9	0	0	0	0	.303	.324	.758	1.081
18	Astros	6/24/2012	1-0	HOU	vs	CLE	W 7-1	1.000	33	7	12	3	0	2	6	2	0	3	0	0	35	21	5	0	0	0	2	.364	.400	.636	1.036
19	Astros	4/19/2013	1-0	HOU	vs	CLE	W 3-2	1.000	29	3	6	0	0	2	3	3	0	9	3	0	33	12	2	1	0	0	0	.207	.281	.414	.695
20	Astros	4/20/2013	0-1	HOU	vs	CLE	L 6-19	.000	37	6	11	3	0	2	6	3	1	10	0	0	41	20	5	0	0	0	0	.297	.366	.541	.906
21	Astros	4/21/2013	0-1	HOU	vs	CLE	L 4-5	.000	32	4	8	1	1	1	4	4	1	7	0	0	39	14	3	1	1	1	0	.250	.342	.438	.780
22	Astros	9/19/2013	0-1	HOU	@	CLE	L 1-2	.000	38	1	9	3	0	0	1	1	1	13	0	1	41	12	3	0	1	0	0	.237	.268	.316	.584
23	Astros	9/20/2013	0-1	HOU	@	CLE	L 1-2	.000	23	1	4	0	1	1	1	2	0	7	0	1	25	9	2	0	0	0	1	.174	.240	.391	.631
24	Astros	9/21/2013	0-1	HOU	@	CLE	L 1-4	.000	31	1	5	1	0	1	1	2	0	12	0	0	33	9	2	0	0	0	1	.161	.212	.290	.502
25	Astros	9/22/2013	0-1	HOU	@	CLE	L 2-9	.000	33	2	9	2	0	1	1	2	0	12	0	1	35	14	3	0	0	0	1	.273	.314	.424	.739
	Total		46-45					.505	3,085	384	748	158	11	102	367	315	27	810	59	29	3,471	1,234	271	21	23	14	66	.242	.316	.400	.716