The Houston Astros put up their most runs in a game against an AL team against the Orioles on August 10, 2019, with 23 runs.

Interpreted as:

astros r in a regular-season game record vs al

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Astros	23	8/10/2019	HOU	@	BAL	W 23-2	50	25	7	0	6	21	2	0	4	0	0	52	50	13	0	0	0	3	.500	.519	1.000	1.519
2	Astros	21	8/18/2022	HOU	@	CWS	W 21-5	51	25	5	0	4	21	4	0	9	1	0	55	42	9	0	0	0	1	.490	.527	.824	1.351
3	Astros	21	9/8/2019	HOU	vs	SEA	W 21-1	47	22	11	0	2	19	7	1	8	0	0	55	39	13	0	0	0	0	.468	.545	.830	1.375
4	Astros	19	7/9/2017	HOU	@	TOR	W 19-1	45	17	4	0	5	16	8	1	7	1	0	54	36	9	0	0	0	1	.378	.481	.800	1.281
5	Astros	17	8/27/2023	HOU	@	DET	W 17-4	52	25	4	1	4	16	6	0	5	0	0	58	43	9	0	0	0	1	.481	.534	.827	1.361
6	Astros	17	7/29/2023	HOU	vs	TBR	W 17-4	42	18	3	1	5	17	6	0	7	0	0	48	38	9	0	0	0	0	.429	.500	.905	1.405
7	Astros	17	5/31/2017	HOU	@	MIN	W 17-6	44	19	2	0	6	16	7	0	3	1	0	52	39	8	0	1	1	0	.432	.500	.886	1.386
8	Astros	17	6/30/1998	HOU	vs	CWS	W 17-2	39	18	3	0	4	17	3	0	7	0	0	43	33	7	0	1	0	2	.462	.488	.846	1.335
9	Astros	16	4/24/2021	HOU	vs	LAA	W 16-2	42	18	7	1	3	14	5	1	7	0	0	48	36	11	0	0	1	2	.429	.500	.857	1.357
10	Astros	16	5/7/2018	HOU	@	OAK	W 16-2	45	20	5	0	3	14	6	0	4	0	0	51	34	8	0	0	0	2	.444	.510	.756	1.265
11	Astros	16	8/4/2017	HOU	vs	TOR	W 16-7	40	18	5	0	5	16	7	0	1	0	0	47	38	10	0	0	0	2	.450	.532	.950	1.482
12	Astros	16	5/29/2017	HOU	@	MIN	W 16-8	44	18	4	0	3	15	5	1	6	0	0	50	31	7	0	0	0	0	.409	.480	.705	1.185
13	Astros	16	5/4/2016	HOU	vs	MIN	W 16-4	38	14	5	0	3	16	7	0	8	0	0	46	28	8	1	0	0	0	.368	.467	.737	1.204
14	Astros	16	4/9/2013	HOU	@	SEA	W 16-9	47	22	3	0	5	15	6	0	10	1	0	53	40	8	0	0	0	2	.468	.528	.851	1.379
15	Astros	15	9/13/2021	HOU	@	TEX	W 15-1	42	16	3	0	5	15	5	1	8	0	0	48	34	8	0	0	0	1	.381	.458	.810	1.268
16	Astros	15	8/21/2021	HOU	vs	SEA	W 15-1	38	15	5	2	2	14	3	0	5	0	0	42	30	9	0	1	0	0	.395	.429	.789	1.218
17	Astros	15	9/9/2019	HOU	vs	OAK	W 15-0	39	17	0	1	7	14	2	0	2	0	0	41	40	8	0	0	0	3	.436	.463	1.026	1.489
18	Astros	15	8/27/2019	HOU	vs	TBR	W 15-1	40	18	4	1	3	14	3	2	7	0	1	46	33	8	0	1	0	0	.450	.500	.825	1.325
19	Astros	15	6/14/2019	HOU	vs	TOR	W 15-2	35	12	1	0	4	15	7	1	11	2	0	44	25	5	0	1	0	0	.343	.455	.714	1.169
20	Astros	15	5/12/2019	HOU	vs	TEX	W 15-5	43	18	3	1	4	14	2	0	8	0	0	45	35	8	0	0	0	0	.419	.444	.814	1.258
21	Astros	15	8/19/2016	HOU	@	BAL	W 15-8	43	18	4	0	4	15	5	1	12	1	1	49	34	8	0	0	0	1	.419	.490	.791	1.280
22	Astros	15	8/11/2016	HOU	@	MIN	W 15-7	46	19	3	0	1	13	6	1	5	0	0	54	25	4	0	1	0	1	.413	.481	.543	1.025
23	Astros	15	8/25/2015	HOU	@	NYY	W 15-1	43	15	4	1	3	14	8	0	4	0	0	51	30	8	0	0	0	0	.349	.451	.698	1.149
24	Astros	14	4/11/2025	HOU	vs	LAA	W 14-3	38	17	1	0	3	13	8	0	3	3	0	48	27	4	0	2	0	0	.447	.521	.711	1.231
25	Astros	14	6/21/2024	HOU	vs	BAL	W 14-11	39	14	6	0	1	12	4	0	10	0	0	43	23	7	0	0	0	1	.359	.419	.590	1.008