The Houston Astros have a record of 53-45 in the regular-season and playoffs against the Twins all-time.

	TEAM	DATE	REC	TM		OPP	RESULT	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Astros	6/13/1997	0-1	HOU	vs	MIN	L 1-8	.000	32	1	6	0	0	1	1	1	0	5	0	0	33	9	1	0	0	0	0	.188	.212	.281	.493
2	Astros	6/14/1997	0-1	HOU	vs	MIN	L 1-6	.000	33	1	9	1	0	1	1	3	0	6	2	0	36	13	2	0	0	0	3	.273	.333	.394	.727
3	Astros	6/15/1997	1-0	HOU	vs	MIN	W 3-2	1.000	27	3	6	1	0	0	2	6	0	5	1	0	35	7	1	2	0	0	2	.222	.364	.259	.623
4	Astros	6/22/1998	0-1	HOU	vs	MIN	L 3-5	.000	30	3	4	0	0	1	3	3	1	5	1	0	34	7	1	0	0	0	1	.133	.235	.233	.469
5	Astros	6/23/1998	1-0	HOU	vs	MIN	W 9-0	1.000	35	9	13	3	0	0	8	4	0	7	2	0	39	16	3	0	0	0	2	.371	.436	.457	.893
6	Astros	6/4/1999	1-0	HOU	@	MIN	W 7-6	1.000	39	7	14	4	0	2	7	2	0	2	2	0	43	24	6	1	1	0	0	.359	.381	.615	.996
7	Astros	6/5/1999	1-0	HOU	@	MIN	W 6-5	1.000	34	6	9	4	0	1	5	6	0	7	0	0	40	16	5	0	0	0	2	.265	.375	.471	.846
8	Astros	6/6/1999	0-1	HOU	@	MIN	L 6-13	.000	36	6	12	1	0	2	6	5	0	6	2	1	41	19	3	0	0	0	3	.333	.415	.528	.942
9	Astros	6/5/2000	1-0	HOU	vs	MIN	W 8-2	1.000	34	8	11	4	0	2	8	1	1	3	0	0	37	21	6	0	1	0	2	.324	.351	.618	.969
10	Astros	6/6/2000	0-1	HOU	vs	MIN	L 1-3	.000	32	1	6	2	0	0	1	3	0	7	0	0	36	8	2	1	0	0	0	.188	.257	.250	.507
11	Astros	6/7/2000	0-1	HOU	vs	MIN	L 0-2	.000	32	0	6	2	0	0	0	1	1	12	0	0	35	8	2	1	0	0	0	.188	.235	.250	.485
12	Astros	6/12/2001	0-1	HOU	@	MIN	L 0-7	.000	31	0	4	1	0	0	0	0	0	7	0	0	31	5	1	0	0	0	0	.129	.129	.161	.290
13	Astros	6/13/2001	0-1	HOU	@	MIN	L 1-3	.000	32	1	6	2	0	1	1	0	0	3	0	0	33	11	3	1	0	0	1	.188	.188	.344	.531
14	Astros	6/14/2001	1-0	HOU	@	MIN	W 8-3	1.000	37	8	16	4	0	3	8	2	0	5	0	1	41	29	7	2	0	0	3	.432	.462	.784	1.245
15	Astros	6/20/2006	0-1	HOU	vs	MIN	L 5-6	.000	37	5	9	0	0	3	5	0	0	8	0	0	37	18	3	0	0	0	1	.243	.243	.486	.730
16	Astros	6/21/2006	1-0	HOU	vs	MIN	W 5-3	1.000	32	5	9	3	0	1	5	2	0	5	0	0	36	15	4	1	1	0	0	.281	.314	.469	.783
17	Astros	6/22/2006	0-1	HOU	vs	MIN	L 2-4	.000	29	2	5	0	0	1	2	2	0	9	0	0	31	8	1	0	0	0	3	.172	.226	.276	.502
18	Astros	6/19/2009	0-1	HOU	@	MIN	L 2-5	.000	27	2	5	0	0	1	2	4	0	9	1	2	33	8	1	1	1	0	1	.185	.281	.296	.578
19	Astros	6/20/2009	1-0	HOU	@	MIN	W 6-5	1.000	34	6	9	4	0	2	6	1	0	7	0	0	36	19	6	1	0	0	1	.265	.286	.559	.845
20	Astros	6/21/2009	1-0	HOU	@	MIN	W 4-1	1.000	36	4	11	3	0	0	4	1	0	1	1	0	38	14	3	0	1	0	1	.306	.316	.389	.705
21	Astros	8/2/2013	0-1	HOU	@	MIN	L 3-4	.000	41	3	7	2	0	0	3	5	1	11	1	1	48	9	2	1	0	0	1	.171	.277	.220	.496
22	Astros	8/3/2013	0-1	HOU	@	MIN	L 4-6	.000	37	4	10	2	0	1	4	2	0	12	2	0	39	15	3	0	0	0	0	.270	.308	.405	.713
23	Astros	8/4/2013	0-1	HOU	@	MIN	L 2-3	.000	35	2	9	0	0	0	2	5	0	8	2	0	40	9	0	0	0	0	0	.257	.350	.257	.607
24	Astros	9/2/2013	0-1	HOU	vs	MIN	L 6-10	.000	37	6	13	3	0	0	6	3	0	10	2	2	40	16	3	0	0	0	0	.351	.400	.432	.832
25	Astros	9/3/2013	0-1	HOU	vs	MIN	L 6-9	.000	41	6	10	0	0	2	6	4	1	7	0	1	46	16	2	0	0	0	3	.244	.326	.390	.716
	Total		53-45					.541	3,380	512	915	181	2	138	488	313	36	750	52	19	3,779	1,514	321	18	32	3	84	.271	.336	.448	.784