Babe Ruth crushed his most home runs in a game on May 25, 1935 and on May 21, 1930, with 3 home runs.

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Assumption:All-time
Data note: Home Runs: player game data may be incomplete before 1901
Data note: Data: Retrosheet

	NAME	HR	DATE	TM		OPP	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	GIDP
1	Babe Ruth B. Ruth	3	5/25/1935	BSN	@	PIT	4	3	4	0	0	6	0	0	0	0	0	4	13	3	0	0
2	Babe Ruth B. Ruth	3	5/21/1930	NYY	@	PHA	4	3	3	0	0	6	0	0	0	0	0	4	12	3	0
3	Babe Ruth B. Ruth	2	5/5/1934	NYY	vs	DET	4	2	2	0	0	5	0	0	0	0	0	4	8	2	0
4	Babe Ruth B. Ruth	2	7/15/1933	NYY	vs	CWS	5	2	2	0	0	3	0	0	0	0	0	5	8	2	0
5	Babe Ruth B. Ruth	2	7/9/1933	NYY	vs	DET	4	3	3	0	0	4	1	0	1	0	0	5	9	2	0
6	Babe Ruth B. Ruth	2	6/10/1933	NYY	@	PHA	5	2	2	0	0	3	0	0	2	0	0	5	8	2	0
7	Babe Ruth B. Ruth	2	5/28/1933	NYY	vs	CWS	3	2	2	0	0	3	2	0	0	0	0	5	8	2	0
8	Babe Ruth B. Ruth	2	7/28/1932	NYY	@	CLE	4	2	3	1	0	7	1	0	0	0	0	5	10	3	0
9	Babe Ruth B. Ruth	2	6/12/1932	NYY	@	CLE	4	3	3	1	0	6	1	0	1	0	0	5	10	3	0
10	Babe Ruth B. Ruth	2	5/21/1932	NYY	vs	WSH	4	2	2	0	0	6	1	0	1	0	0	5	8	2	0
11	Babe Ruth B. Ruth	2	4/12/1932	NYY	@	PHA	5	2	3	0	0	5	0	0	1	0	0	5	9	2	0
12	Babe Ruth B. Ruth	2	9/25/1931	NYY	vs	WSH	4	2	2	0	0	2	0	0	0	0	0	4	8	2	0
13	Babe Ruth B. Ruth	2	9/17/1931	NYY	vs	SLA	5	3	2	0	0	3	0	0	0	0	0	5	8	2	0
14	Babe Ruth B. Ruth	2	9/7/1931	NYY	@	PHA	4	2	3	0	0	3	1	0	0	0	0	5	9	2	0
15	Babe Ruth B. Ruth	2	7/22/1931	NYY	vs	DET	4	3	3	0	0	4	1	0	0	0	0	5	9	2	0
16	Babe Ruth B. Ruth	2	4/20/1931	NYY	vs	PHA	4	2	2	0	0	4	0	0	1	0	0	4	8	2	0
17	Babe Ruth B. Ruth	2	9/27/1930	NYY	@	PHA	4	2	2	0	0	5	1	0	0	0	0	6	8	2	1
18	Babe Ruth B. Ruth	2	8/1/1930	NYY	@	BSA	3	2	3	1	0	3	2	0	0	0	0	5	10	3	0
19	Babe Ruth B. Ruth	2	6/28/1930	NYY	vs	CLE	4	3	2	0	0	2	1	0	0	0	1	5	8	2	0
20	Babe Ruth B. Ruth	2	6/25/1930	NYY	vs	SLA	5	3	3	0	0	4	0	0	0	0	0	5	9	2	0
21	Babe Ruth B. Ruth	2	5/22/1930	NYY	@	PHA	5	2	3	0	0	3	0	0	1	0	0	5	9	2	0
22	Babe Ruth B. Ruth	2	8/31/1929	NYY	vs	WSH	6	2	3	0	0	5	0	0	1	0	0	6	9	2	0
23	Babe Ruth B. Ruth	2	8/25/1929	NYY	@	SLA	4	2	3	0	0	2	0	0	0	0	0	4	9	2	0
24	Babe Ruth B. Ruth	2	8/6/1929	NYY	vs	WSH	4	2	2	0	0	7	0	0	0	0	0	4	8	2	0
25	Babe Ruth B. Ruth	2	6/29/1929	NYY	@	PHA	4	2	2	0	0	3	1	0	1	0	0	5	8	2	0

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Babe Ruth crushed his most home runs in a game on May 25, 1935 and on May 21, 1930, with 3 home runs.

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