Babe Ruth has smashed the most career home runs against the Red Sox, with 90 home runs.

Interpreted as:

best career home runs by a player vs red sox

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Babe Ruth B. Ruth	90	293	1,030	285	347	61	13	272	240	4	139	22		1,290	704	164	16				.337	.464	.683	1.147
2	Lou Gehrig L. Gehrig	70	312	1,149	280	404	82	22	317	211	9	113	21		1,388	740	174	19			2	.352	.456	.644	1.100
3	Mickey Mantle M. Mantle	69	299	972	211	296	42	9	195	230	3	230	20	5	1,209	563	120	3	1	11	13	.305	.439	.579	1.018
4	Al Kaline A. Kaline	62	349	1,300	220	403	78	7	220	151	9	136	17	8	1,471	681	147	7	4	19	28	.310	.385	.524	.908
5	Harmon Killebrew H. Killebrew	61	268	913	163	260	43	5	199	172	6	210	1	2	1,105	496	109	0	14	14	30	.285	.396	.543	.940
6	Alex Rodriguez A. Rodriguez	59	265	996	195	282	46	3	170	133	21	223	48	8	1,159	511	108	0	9	6	27	.283	.376	.513	.889
7	Reggie Jackson R. Jackson	51	236	832	123	221	50	3	149	121	6	223	25	5	964	430	104	0	5	16	11	.266	.361	.517	.878
8	Norm Cash N. Cash	49	252	845	139	249	37	6	145	137	6	126	3	3	992	445	92	1	3	11	21	.295	.396	.527	.922
9	Rocky Colavito R. Colavito	48	227	770	137	217	34	1	137	133	3	101	2	3	911	397	83	1	4	4	19	.282	.388	.516	.903
10	Joe DiMaggio J. DiMaggio	46	253	967	193	323	58	15	222	131	2	63	4	0	1,103	549	119	3			18	.334	.415	.568	.982
11	Gus Zernial G. Zernial	44	189	638	95	167	30	4	128	56	1	122	0	1	698	337	78	0	3	1	21	.262	.321	.528	.849
12	Rudy York R. York	44	200	754	128	233	50	5	165	88	1	97	6		848	425	99	5			19	.309	.382	.564	.946
13	Jose Bautista J. Bautista	43	156	556	94	131	19	1	103	91	3	128	7	3	659	281	63	0	9	2	13	.236	.341	.505	.847
14	Frank Thomas F. Thomas	43	163	577	105	183	34	0	126	108	5	114	3	2	703	346	77	0	13	17	11	.317	.421	.600	1.021
15	Joe Gordon J. Gordon	43	226	837	140	225	40	8	153	105	4	120	14		952	410	91	6			27	.269	.353	.490	.843
16	Bob Johnson B. Johnson	43	219	795	154	229	45	7	137	145	3	102	13		949	417	95	6			8	.288	.400	.525	.924
17	Jose Canseco J. Canseco	42	129	481	102	137	23	0	108	65	9	141	17	10	556	286	65	0	1	3	13	.285	.379	.595	.974
18	Hank Greenberg H. Greenberg	42	182	706	130	211	55	4	174	98	3	133	5		811	400	101	4			13	.299	.387	.567	.953
19	Willie Horton W. Horton	40	190	712	85	201	27	5	120	50	10	135	2	4	782	358	72	4	6	9	16	.282	.335	.503	.838
20	Al Simmons A. Simmons	40	294	1,158	220	383	80	23	254	88	3	86	22		1,264	629	143	15			2	.331	.380	.543	.923
21	Boog Powell B. Powell	39	234	795	112	232	41	1	145	120	3	129	0	1	927	392	81	2	7	23	22	.292	.384	.493	.877
22	Roy Sievers R. Sievers	38	208	754	127	239	47	5	160	124	1	93	3	1	887	410	90	0	8	13	26	.317	.410	.544	.954
23	Yogi Berra Y. Berra	38	296	1,097	147	297	46	9	185	87	4	66	3	5	1,189	475	93	1	0	7	25	.271	.327	.433	.760
24	Ken Keltner K. Keltner	38	219	829	144	253	53	15	169	105	5	80	5		950	450	106	11			23	.305	.387	.543	.929
25	Jason Giambi J. Giambi	37	185	621	96	160	34	2	117	112	19	152	1	0	762	309	73	1	9	9	15	.258	.382	.498	.880