The Cleveland Guardians had the best record by a team in September 2022, with a record of 21-8.

	TEAM	REC	MONTH	W%	G	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Guardians	21-8	September 2022	.724	29	21	8	1,028	131	271	36	8	23	121	85	22	195	31	7	1,149	392	67	7	7	20	25	.264	.331	.381	.712
2	Astros	18-8	September 2022	.692	26	18	8	883	126	221	43	1	37	121	81	12	174	18	5	985	377	81	2	7	5	19	.250	.319	.427	.746
3	Braves	18-8	September 2022	.692	26	18	8	870	123	219	38	1	43	117	71	10	235	12	6	958	388	82	0	7	3	17	.252	.313	.446	.759
4	Yankees	17-8	September 2022	.680	25	17	8	847	134	212	38	0	39	125	95	8	235	20	5	958	367	77	1	7	9	17	.250	.329	.433	.762
5	Dodgers	19-9	September 2022	.679	28	19	9	956	140	233	51	6	37	138	103	13	250	13	3	1,080	407	94	2	6	6	11	.244	.324	.426	.749
6	Giants	18-10	September 2022	.643	28	18	10	938	126	228	41	6	33	118	88	11	282	4	4	1,046	380	80	2	7	1	18	.243	.313	.405	.718
7	Blue Jays	18-10	September 2022	.643	28	18	10	966	145	257	56	4	35	141	97	9	209	15	6	1,077	426	95	0	5	2	27	.266	.337	.441	.778
8	Cubs	15-11	September 2022	.577	26	15	11	834	86	192	37	6	19	81	72	15	245	20	4	935	298	62	9	5	1	21	.230	.301	.357	.659
9	Cardinals	15-11	September 2022	.577	26	15	11	843	97	188	46	0	30	94	84	9	181	15	3	941	324	76	1	4	2	19	.223	.299	.384	.683
10	Mets	15-11	September 2022	.577	26	15	11	883	134	232	42	4	30	129	98	23	184	14	2	1,013	372	76	1	8	6	24	.263	.349	.421	.770
11	Angels	14-12	September 2022	.538	26	14	12	889	105	228	45	3	37	103	63	4	244	11	1	965	390	85	3	6	2	13	.256	.307	.439	.745
12	Mariners	14-12	September 2022	.538	26	14	12	855	118	187	38	3	39	116	111	15	227	12	5	986	348	80	0	5	2	25	.219	.317	.407	.724
13	Brewers	15-13	September 2022	.536	28	15	13	925	119	214	54	2	32	113	88	13	259	16	3	1,033	368	88	2	5	4	16	.231	.306	.398	.703
14	Padres	13-12	September 2022	.520	25	13	12	845	100	192	39	1	28	95	83	9	198	9	2	947	317	68	4	6	3	12	.227	.301	.375	.676
15	White Sox	14-13	September 2022	.519	27	14	13	947	126	234	45	1	34	123	56	11	232	13	2	1,024	383	80	2	8	1	18	.247	.295	.404	.699
16	Rays	14-14	September 2022	.500	28	14	14	935	108	224	58	1	17	104	80	14	219	19	5	1,035	335	76	1	5	2	12	.240	.308	.358	.666
17	Tigers	13-13	September 2022	.500	26	13	13	879	98	210	39	6	26	94	58	11	222	5	2	960	339	71	4	8	4	19	.239	.292	.386	.678
18	Orioles	13-15	September 2022	.464	28	13	15	949	121	232	38	8	36	115	87	9	230	15	4	1,049	394	82	2	2	2	17	.244	.313	.415	.728
19	Red Sox	12-14	September 2022	.462	26	12	14	859	127	223	51	1	27	123	107	13	223	6	3	988	357	79	3	6	3	29	.260	.348	.416	.764
20	Phillies	11-14	September 2022	.440	25	11	14	841	101	213	37	4	32	100	75	6	214	15	7	933	354	73	1	10	3	20	.253	.315	.421	.736
21	Diamondbacks	11-17	September 2022	.393	28	11	17	923	110	205	42	2	29	104	70	12	255	31	6	1,017	338	73	1	11	1	20	.222	.282	.366	.649
22	Royals	10-16	September 2022	.385	26	10	16	866	103	213	47	6	21	99	74	6	194	16	8	954	335	74	3	5	2	13	.246	.308	.387	.695
23	Nationals	10-16	September 2022	.385	26	10	16	898	98	231	43	6	21	94	65	7	209	16	5	983	349	70	4	9	3	18	.257	.309	.389	.698
24	Pirates	10-17	September 2022	.370	27	10	17	891	103	201	39	4	27	98	86	14	264	22	4	1,003	329	70	4	8	3	14	.226	.301	.369	.671
25	Marlins	10-17	September 2022	.370	27	10	17	886	93	208	42	0	24	87	66	13	247	10	5	973	322	66	1	7	0	22	.235	.295	.363	.659