The Texas Rangers had the highest run differential by a team in May 2023, with a differential of 59 runs.

	TEAM	DIFF	MONTH	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rangers	59	May 2023	27	.667	18	9	973	168	278	57	5	33	158	81	7	239	18	5	1,075	444	95	3	11	4	16	.286	.341	.456	.798
2	Dodgers	40	May 2023	28	.643	18	10	972	173	253	64	5	49	165	115	11	232	19	4	1,111	474	118	0	13	7	14	.260	.341	.488	.829
3	Yankees	38	May 2023	29	.655	19	10	989	157	249	40	5	53	156	94	7	233	18	7	1,100	458	98	2	8	5	18	.252	.319	.463	.782
4	Astros	27	May 2023	27	.630	17	10	886	118	215	47	3	31	112	79	12	212	9	5	986	361	81	1	8	3	25	.243	.311	.407	.718
5	Mariners	23	May 2023	28	.607	17	11	938	129	223	47	2	30	122	100	16	262	14	5	1,059	364	79	0	5	2	15	.238	.320	.388	.708
6	Giants	21	May 2023	29	.586	17	12	977	131	247	52	2	30	130	91	7	260	15	4	1,087	393	84	4	8	1	16	.253	.319	.402	.721
7	Cardinals	20	May 2023	28	.536	15	13	956	150	232	48	3	44	144	101	8	232	25	5	1,073	418	95	1	7	5	15	.243	.318	.437	.755
8	Twins	20	May 2023	27	.444	12	15	933	122	215	43	1	36	114	115	15	299	21	3	1,068	368	80	2	3	4	18	.230	.324	.394	.718
9	Diamondbacks	18	May 2023	27	.630	17	10	921	137	238	43	5	40	128	101	5	204	28	3	1,041	411	88	7	7	4	16	.258	.333	.446	.779
10	Rays	16	May 2023	29	.586	17	12	955	145	242	46	5	42	139	103	16	235	52	7	1,082	424	93	2	6	0	25	.253	.334	.444	.778
11	Braves	15	May 2023	29	.517	15	14	989	144	254	53	1	51	142	82	15	232	17	5	1,094	462	105	0	8	5	26	.257	.321	.467	.788
12	Padres	12	May 2023	26	.385	10	16	849	103	180	37	1	29	97	120	9	234	27	6	986	306	67	3	5	3	17	.212	.314	.360	.675
13	White Sox	10	May 2023	29	.517	15	14	979	133	243	48	6	32	131	69	8	234	13	3	1,070	399	86	5	9	6	22	.248	.300	.408	.708
14	Blue Jays	9	May 2023	28	.393	11	17	998	134	273	56	5	31	123	83	6	212	23	5	1,094	432	92	1	6	1	28	.274	.331	.433	.764
15	Orioles	3	May 2023	28	.571	16	12	960	134	238	54	7	31	131	94	8	233	15	5	1,070	399	92	3	5	3	21	.248	.319	.416	.734
16	Nationals	-2	May 2023	29	.483	14	15	993	136	273	57	5	29	130	79	15	208	15	3	1,093	427	91	3	3	1	22	.275	.337	.430	.767
17	Red Sox	-3	May 2023	26	.500	13	13	896	122	244	62	2	26	121	73	10	211	20	5	984	388	90	2	3	1	21	.272	.333	.433	.766
18	Angels	-6	May 2023	28	.536	15	13	960	132	253	46	4	39	130	83	14	254	12	3	1,069	424	89	0	12	3	24	.264	.327	.442	.769
19	Royals	-6	May 2023	27	.370	10	17	913	125	224	47	6	36	123	82	14	244	21	4	1,021	391	89	2	10	3	9	.245	.314	.428	.742
20	Rockies	-7	May 2023	28	.536	15	13	943	141	256	68	6	25	135	88	5	226	13	4	1,047	411	99	1	10	1	22	.271	.334	.436	.769
21	Reds	-8	May 2023	27	.519	14	13	932	131	248	61	5	24	128	93	10	244	24	8	1,045	391	90	3	7	1	19	.266	.337	.420	.756
22	Tigers	-9	May 2023	27	.593	16	11	912	116	218	43	1	26	112	106	10	212	18	1	1,034	341	70	0	6	1	17	.239	.323	.374	.697
23	Marlins	-10	May 2023	27	.481	13	14	938	110	251	38	6	28	103	82	6	221	18	7	1,039	385	72	8	5	7	32	.268	.329	.410	.739
24	Guardians	-15	May 2023	27	.444	12	15	884	92	206	44	5	16	86	72	5	183	13	3	968	308	65	1	6	6	20	.233	.293	.348	.641
25	Mets	-16	May 2023	29	.483	14	15	972	127	243	32	7	37	122	87	15	204	15	3	1,084	400	76	3	7	1	16	.250	.319	.412	.731